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2'-5'-oligoadenylate trimer
Known as:
adenylyl-(2'-5')-adenylyl-(2'-5')adenylic acid
, PAPAPA
, (5'-O-phosphoryladenylyl)(2'-5')adenylyl(2'-5')adenosine
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National Institutes of Health
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Broader (1)
2',5'-oligoadenylate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
On the discovery of interferon-inducible, double-stranded RNA activated enzymes: the 2'-5'oligoadenylate synthetases and the protein kinase PKR.
A. Hovanessian
Cytokine & growth factor reviews
2007
Corpus ID: 24316477
Highly Cited
2004
Highly Cited
2004
Structural basis for recognition of 2′,5′‐linked oligoadenylates by human ribonuclease L
N. Tanaka
,
M. Nakanishi
,
Y. Kusakabe
,
Yoshikuni Goto
,
Y. Kitade
,
Kazuo T. Nakamura
EMBO Journal
2004
Corpus ID: 33479216
An interferon‐induced endoribonuclease, ribonuclease L (RNase L), is implicated in both the molecular mechanism of action of…
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Highly Cited
2003
Highly Cited
2003
Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.
Y. Xiang
,
Zhengfu Wang
,
+7 authors
R. Silverman
Cancer Research
2003
Corpus ID: 8891152
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific…
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Review
2003
Review
2003
Implications for RNase L in prostate cancer biology.
R. Silverman
Biochemistry
2003
Corpus ID: 40021834
Recently, the interferon (IFN) antiviral pathways and prostate cancer genetics and have surprisingly converged on a single-strand…
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Highly Cited
1995
Highly Cited
1995
2-5A-dependent RNase Molecules Dimerize during Activation by 2-5A (*)
B. Dong
,
R. Silverman
Journal of Biological Chemistry
1995
Corpus ID: 25928810
2-5A-dependent RNase is an interferon-inducible enzyme that requires 5′-phosphorylated, 2′,5′-linked oligoadenylates (2-5A) for…
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Highly Cited
1993
Highly Cited
1993
Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action
Aimin Zhou
,
B. Hassel
,
R. Silverman
Cell
1993
Corpus ID: 45773755
Highly Cited
1993
Highly Cited
1993
Oligoribonucleotides containing 2',5'-phosphodiester linkages exhibit binding selectivity for 3',5'-RNA over 3',5'-ssDNA.
P. A. Giannaris
,
M. Damha
Nucleic Acids Research
1993
Corpus ID: 22499937
Oligoribonucleotides containing 2',5'-phosphodiester linkages have been synthesized on a solid support by the 'silyl…
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Highly Cited
1988
Highly Cited
1988
Characterization of 69- and 100-kDa forms of 2-5A-synthetase from interferon-treated human cells.
A. Hovanessian
,
J. Svab
,
I. Marié
,
N. Robert
,
S. Chamaret
,
A. Laurent
Journal of Biological Chemistry
1988
Corpus ID: 28429031
Highly Cited
1964
Highly Cited
1964
RNA Codewords and Protein Synthesis
M. Nirenberg
,
P. Leder
Science
1964
Corpus ID: 7127820
A rapid, sensitive method is described for measuring C14-aminoacyl-sRNA interactions with ribosomes which are specifically…
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Highly Cited
1964
Highly Cited
1964
RNA CODEWORDS AND PROTEIN SYNTHESIS. II. NUCLEOTIDE SEQUENCE OF A VALINE RNA CODEWORD.
P. Leder
,
M. Nirenberg
Proceedings of the National Academy of Sciences…
1964
Corpus ID: 15559832
After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the…
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