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2'-5'-oligoadenylate trimer

Known as: adenylyl-(2'-5')-adenylyl-(2'-5')adenylic acid, PAPAPA, (5'-O-phosphoryladenylyl)(2'-5')adenylyl(2'-5')adenosine 
National Institutes of Health

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2',5'-oligoadenylate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3'-O,4'-C-methylene-linked alpha-L-ribonucleotides.
2005
2005
Functional Characterization of 2′,5′-Linked Oligoadenylate Binding Determinant of Human RNase L*
RNase L is activated by the binding of unusual 2′,5′-linked oligoadenylates (2-5A) and acts as the effector enzyme of the 2-5A… 
2002
2002
2',5'-oligoadenylate synthetase from a lower invertebrate, the marine sponge Geodia cydonium, does not need dsRNA for its enzymatic activity.
2002
2002
Comparative study on the biological properties of 2',5'-oligoadenylate derivatives with purified human RNase L expressed in E. coli.
An endoribonuclease, RNase L, which is activated in the presence of 2',5'-linked oligoadenylates, p(1-3)A(2'p5'A)(>2), is the… 
1999
1999
2,5-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L.
Review
1999
Review
1999
Controlling gene expression with 2-5A antisense.
Recent work has demonstrated that the activity of a ubiquitous cellular enzyme, ribonuclease L (RNase L), can be harnessed to… 
1984
1984
Oligonucleotide structural parameters that influence binding of 5'-O-triphosphoadenylyl-(2'----5')-adenylyl-(2'----5')-adenosine to the 5'-O-triphosphoadenylyl-(2'----5')-adenylyl-(2'----5…
A number of 2',5'-linked oligoadenylates and their analogues were prepared and evaluated for their ability to interact with the 5… 
Highly Cited
1964
Highly Cited
1964
RNA CODEWORDS AND PROTEIN SYNTHESIS. II. NUCLEOTIDE SEQUENCE OF A VALINE RNA CODEWORD.
After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the… 
1962
1962
The polymerization of 8-azaguanosine 5-diphosphate by polynucleotide phosphorylase.
1960
1960
The polymerization of guanosine diphosphate by polynucletide phosphorylase.
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