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2'-5'-oligoadenylate trimer

Known as: adenylyl-(2'-5')-adenylyl-(2'-5')adenylic acid, PAPAPA, (5'-O-phosphoryladenylyl)(2'-5')adenylyl(2'-5')adenosine 
National Institutes of Health

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2',5'-oligoadenylate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
On the discovery of interferon-inducible, double-stranded RNA activated enzymes: the 2'-5'oligoadenylate synthetases and the protein kinase PKR.
Highly Cited
2004
Highly Cited
2004
Structural basis for recognition of 2′,5′‐linked oligoadenylates by human ribonuclease L
An interferon‐induced endoribonuclease, ribonuclease L (RNase L), is implicated in both the molecular mechanism of action of… 
Highly Cited
2003
Highly Cited
2003
Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… 
Review
2003
Review
2003
Implications for RNase L in prostate cancer biology.
Recently, the interferon (IFN) antiviral pathways and prostate cancer genetics and have surprisingly converged on a single-strand… 
Highly Cited
1995
Highly Cited
1995
2-5A-dependent RNase Molecules Dimerize during Activation by 2-5A (*)
2-5A-dependent RNase is an interferon-inducible enzyme that requires 5′-phosphorylated, 2′,5′-linked oligoadenylates (2-5A) for… 
Highly Cited
1993
Highly Cited
1993
Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action
Highly Cited
1993
Highly Cited
1993
Oligoribonucleotides containing 2',5'-phosphodiester linkages exhibit binding selectivity for 3',5'-RNA over 3',5'-ssDNA.
Oligoribonucleotides containing 2',5'-phosphodiester linkages have been synthesized on a solid support by the 'silyl… 
Highly Cited
1988
Highly Cited
1988
Characterization of 69- and 100-kDa forms of 2-5A-synthetase from interferon-treated human cells.
Highly Cited
1964
Highly Cited
1964
RNA Codewords and Protein Synthesis
A rapid, sensitive method is described for measuring C14-aminoacyl-sRNA interactions with ribosomes which are specifically… 
Highly Cited
1964
Highly Cited
1964
RNA CODEWORDS AND PROTEIN SYNTHESIS. II. NUCLEOTIDE SEQUENCE OF A VALINE RNA CODEWORD.
After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the… 
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