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2'-5'-oligoadenylate trimer

Known as: adenylyl-(2'-5')-adenylyl-(2'-5')adenylic acid, PAPAPA, (5'-O-phosphoryladenylyl)(2'-5')adenylyl(2'-5')adenosine 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
The demonstration that double-stranded (ds) RNA inhibits protein synthesis in cell-free systems prepared from interferon-treated… 
Highly Cited
2006
Highly Cited
2006
The antiviral and antitumor functions of RNase L are enabled by binding to the allosteric effectors 5′-phosphorylated, 2′,5… 
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Review
2003
Review
2003
Recently, the interferon (IFN) antiviral pathways and prostate cancer genetics and have surprisingly converged on a single-strand… 
Highly Cited
2003
Highly Cited
2003
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… 
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Highly Cited
1995
Highly Cited
1995
2-5A-dependent RNase is an interferon-inducible enzyme that requires 5′-phosphorylated, 2′,5′-linked oligoadenylates (2-5A) for… 
Highly Cited
1993
Highly Cited
1993
2-5A-dependent RNAase, an interferon-induced enzyme that is activated by 5'-phosphorylated, 2',5'-linked oligoadenylates (2-5A… 
Highly Cited
1993
Highly Cited
1993
Oligoribonucleotides containing 2',5'-phosphodiester linkages have been synthesized on a solid support by the 'silyl… 
Highly Cited
1988
Highly Cited
1988
The existence of distinct 69- and 100-kDa forms of 2-5A-synthetase in addition to the smaller (40 and 46 kDa) forms has recently… 
Highly Cited
1964
Highly Cited
1964
A rapid, sensitive method is described for measuring C14-aminoacyl-sRNA interactions with ribosomes which are specifically… 
Highly Cited
1964
Highly Cited
1964
After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the… 
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