2'-5'-oligoadenylate trimer

The demonstration that double-stranded (ds) RNA inhibits protein synthesis in cell-free systems prepared from interferon-treated… Expand

The antiviral and antitumor functions of RNase L are enabled by binding to the allosteric effectors 5′-phosphorylated, 2′,5… Expand

An interferon‐induced endoribonuclease, ribonuclease L (RNase L), is implicated in both the molecular mechanism of action of… Expand

The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… Expand

2-5A-dependent RNase is an interferon-inducible enzyme that requires 5′-phosphorylated, 2′,5′-linked oligoadenylates (2-5A) for… Expand

2-5A-dependent RNAase, an interferon-induced enzyme that is activated by 5'-phosphorylated, 2',5'-linked oligoadenylates (2-5A… Expand

Oligoribonucleotides containing 2',5'-phosphodiester linkages have been synthesized on a solid support by the 'silyl… Expand

The existence of distinct 69- and 100-kDa forms of 2-5A-synthetase in addition to the smaller (40 and 46 kDa) forms has recently… Expand

A rapid, sensitive method is described for measuring C14-aminoacyl-sRNA interactions with ribosomes which are specifically… Expand

After the poly-U experiments, the next major challenge was finding out what the remaining codewords were. In this article, the… Expand