2',5'-oligoadenylate

Known as: 2'-5'-Oligoadenylate, oligos, 2'-5' Oligoadenylate 
An oligonucleotide synthesized from adenosine triphosphate (ATP) by enzymes in the 2'-5'-oligoadenylate synthase family. The production of 2'-5… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Oligonucleotides (oligos) have been under clinical development for approximately the past 30 years, beginning with antisense… (More)
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Highly Cited
2013
Highly Cited
2013
Mice carrying mutations in multiple genes are traditionally generated by sequential recombination in embryonic stem cells and/or… (More)
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Highly Cited
2006
Highly Cited
2006
New uniform response criteria are required to adequately assess clinical outcomes in myeloma. The European Group for Blood and… (More)
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Highly Cited
2005
Highly Cited
2005
Biological systems are known to be highly transparent to 700- to 1,100-nm near-infrared (NIR) light. It is shown here that the… (More)
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Highly Cited
2004
Highly Cited
2004
  • Fertility and sterility
  • 2004
Since the 1990 National Institutes of Health-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated… (More)
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Review
2004
Review
2004
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta… (More)
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Highly Cited
2003
Highly Cited
2003
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… (More)
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Highly Cited
2000
Highly Cited
2000
1. Introduction Designing PCR and sequencing primers are essential activities for molecular biologists around the world. This… (More)
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Review
1999
Review
1999
2',5'-Oligoadenylate synthetase (2',5'-OAS) was discovered and characterized as an interferon (IFN)-induced enzyme that in the… (More)
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Highly Cited
1997
Highly Cited
1997
2',5'-Oligoadenylate-dependent RNase L functions in the interferon-inducible, RNA decay pathway known as the 2-5A system. To… (More)
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