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1-hydroxybenzotriazole

Known as: HOBt 
National Institutes of Health

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N-hydroxybenzotriazole

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Triazoles

Papers overview

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2013
2013
Orthogonal chemistry for the synthesis of thiocoraline-triostin hybrids. Exploring their structure-activity relationship.
The natural compounds triostin and thiocoraline are potent antitumor agents that act as DNA bisintercalators. From a… 
2009
2009
Synthesis of O-glycosylated tuftsins by utilizing threonine derivatives containing an unprotected monosaccharide moiety.
Synthesis is described of four tuftsin derivatives containing a D-glucopyranosyl or a D-galactopyranosyl unit covalently linked… 
2009
2009
Effect of tertiary amine on the carbodiimide-mediated peptide synthesis.
The effect of tertiary amine (DIEA) on reaction rate and product purity of a carbodiimide/HOBt-mediated peptide synthesis was… 
2009
2009
Synthesis of phosphopeptides containing O-phosphoserine or O-phosphothreonine.
Peptides containing phosphoserine or phosphothreonine were synthesized by solid phase methods. Phosphoserine and phosphothreonine… 
2007
2007
Multigram solution-phase synthesis of three diastereomeric tripeptidic second-generation dendrons based on (2S,4S)-, (2S,4R)-, and (2R,4S)-4-aminoprolines.
Three diastereomeric second-generation (G2) dendrons were prepared by using (2S,4S)-, (2S,4R)-, and (2R,4S)-4-aminoprolines on… 
2002
2002
Synthesis and cleavage experiments of oligonucleotide conjugates with a diimidazole-derived catalytic center.
Ribonuclease mimics based on diimidazole derived constructs in combination with or without additional amino groups have been… 
2000
2000
Design and synthesis of novel thiazole-containing cross-linked polyamides related to the antiviral antibiotic distamycin.
A family of naturally occurring oligopeptides includes netropsin, distamycin, anthelvencin, kikumycin B, amidinomycin, and… 
Highly Cited
1997
Highly Cited
1997
Versatile Acylation of N-Nucleophiles Using a New Polymer-Supported 1-Hydroxybenzotriazole Derivative.
The synthesis of a new polymer-supported coupling reagent derived from 1-hydroxybenzotriazole is described. An aminomethylated… 
1986
1986
Use of a 1-hydroxybenzotriazole activated phosphorylating reagent towards the synthesis of short RNA fragments in solution.
Evidence will be presented to show that the reagents 3a-c (X = O) obtained by the reaction of 2-chlorophenylphosphorodichloridate… 
Highly Cited
1975
Highly Cited
1975
New useful reagents for peptide synthesis. Insoluble active esters of polystyrene-bound 1-hydroxybenzotriazole.
Insoluble 1-hydroxbenzotriazole-bound polystyrene was prepared through a series of chemical modifications of commercially… 
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