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Adenosine is thought to be a major effector in immunological stimulation of Cl secretion in intestinal epithelia. Previous… Expand 2-[p-(2-carboxyethyl)-phenylethylamino]-5'-N-ethylcarboxamidoadeno sine (CGS 21680) is considered a selective ligand for… Expand Adenosine exerts pronounced biological effects in the heart cell. The role of multiple adenosine receptor subtypes in regulating… Expand The pharmacological actions of methylxanthines such as theophylline and caffeine may be due to blockade of adenosine receptors… Expand 1 The ability of 1,3,8‐substituted xanthines to antagonize the inhibitory effects of adenosine receptor agonists on the amplitude… Expand Characterization of the adenosine A2 receptor has been limited due to the lack of available ligands which have high affinity and… Expand Extracellular ATP and other purinergic agonists were found to inhibit cAMP accumulation by depressing adenylate cyclase as an… Expand Summary: Stable analogues of adenosine were used to investigate the specificity of the receptors mediating its negative… Expand Several adenosine analogs were evaluated for their effects on rate and contractility in guinea pig isolated atria. Among… Expand Adenosine has a significant role in many functions of the central nervous system. Behaviorally, adenosine and adenosine analogs… Expand