Xanthines

Known as: Xanthines [Chemical/Ingredient], xanthine 
Purine bases found in body tissues and fluids and in some plants.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1943-2018
010203019432017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Methylxanthines, including caffeine and theophylline, are among the most widely consumed stimulant drugs in the world. These… (More)
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Highly Cited
1999
Highly Cited
1999
Recombinant human A(2B) adenosine receptors (A(2B)ARs) and receptors extended on the amino terminus with hexahistidine and the… (More)
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Highly Cited
1997
Highly Cited
1997
Four adenosine receptor subtypes of the family of G protein-coupled receptors, designated A1, A2A, A2B and A3 are currently known… (More)
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Highly Cited
1996
Highly Cited
1996
In sensitized subjects, exposure to the mite allergen appears to be only one of several factors leading to asthma. We… (More)
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1996
1996
Trafficking, activation, and kinetics of delta F508-cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR were… (More)
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1993
1993
The pharmacological actions of methylxanthines such as theophylline and caffeine may be due to blockade of adenosine receptors… (More)
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1993
1993
Reactive oxygen metabolites generated from xanthine oxidase play an important role in the pathogenesis of ischemia-induced tissue… (More)
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1991
1991
Xanthine oxidase catalyzes the biotransformation of many drugs, including the thiopurines and methyl-xanthines. We used a… (More)
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1990
1990
1. The ability of 1,3,8-substituted xanthines to antagonize the inhibitory effects of adenosine receptor agonist on the amplitude… (More)
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Highly Cited
1983
Highly Cited
1983
1. The potencies of caffeine and related methylxanthines as adenosine antagonists were assessed with respect to three apparent… (More)
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