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Pentoxifylline

Known as: 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-, Oxpentifylline 
A methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver impairment that occurs in patients with… 
Highly Cited
2011
Highly Cited
2011
The primary aim of this study was to compare the effects of pentoxifylline (PTX) versus placebo on the histological features of… 
Highly Cited
2011
Highly Cited
2011
Background— Sustained benefits of drug-eluting stents in femoropopliteal arteries have not been demonstrated. This prospective… 
Highly Cited
2005
Highly Cited
2005
PURPOSE The primary aim of National Surgical Adjuvant Breast and Bowel Project (NSABP) B-28 was to determine whether four cycles… 
Highly Cited
2003
Highly Cited
2003
PURPOSE Radiation-induced fibrosis (RIF) is a rare morbid complication of radiotherapy, without an established method of… 
Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS An earlier pilot study from our liver unit suggested benefit from treatment with pentoxifylline (PTX), an… 
Highly Cited
1995
Highly Cited
1995
The possibility that appropriately designed chemotherapy could act selectively against p53-defective tumor cells was explored in… 
Highly Cited
1990
Highly Cited
1990
The induction of cachectin/tumor necrosis factor (TNF) synthesis by bacterial endotoxins is a process that entails activation at… 
Review
1987
Review
1987
Pentoxifylline (oxpentifylline) is an orally active haemorheological agent for the treatment of peripheral vascular disease…