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Pentoxifylline

Known as: 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-, Oxpentifylline 
A methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently… Expand
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Review
2018
Review
2018
Diabetic kidney disease (DKD) is a major cause of morbidity and mortality in patients with diabetes mellitus and the leading… Expand
Review
2017
Review
2017
Preamble Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific… Expand
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Review
2017
Review
2017
Jonathan L. Halperin, MD, FACC, FAHA, Chair Glenn N. Levine, MD, FACC, FAHA, Chair-Elect Sana M. Al-Khatib, MD, MHS, FACC… Expand
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Highly Cited
2011
Highly Cited
2011
The primary aim of this study was to compare the effects of pentoxifylline (PTX) versus placebo on the histological features of… Expand
Highly Cited
2005
Highly Cited
2005
PURPOSE The primary aim of National Surgical Adjuvant Breast and Bowel Project (NSABP) B-28 was to determine whether four cycles… Expand
Highly Cited
2003
Highly Cited
2003
PURPOSE Radiation-induced fibrosis (RIF) is a rare morbid complication of radiotherapy, without an established method of… Expand
Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS An earlier pilot study from our liver unit suggested benefit from treatment with pentoxifylline (PTX), an… Expand
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Highly Cited
2000
Highly Cited
2000
PURPOSE We performed a randomized, double-blind, placebo-controlled, multicenter trial to evaluate the relative efficacy and… Expand
Highly Cited
1995
Highly Cited
1995
The possibility that appropriately designed chemotherapy could act selectively against p53-defective tumor cells was explored in… Expand