Adenosine receptors in the nervous system: pathophysiological implications
- J. Ribeiro, A. Sebastião, A. Mendonça
- Biology, PsychologyProgress in neurobiology
- 1 December 2002
Inhibition by ATP of Hippocampal Synaptic Transmission Requires Localized Extracellular Catabolism by Ecto-Nucleotidases into Adenosine and Channeling to Adenosine A1 Receptors
- R. Cunha, A. Sebastião, J. Ribeiro
- Biology, ChemistryJournal of Neuroscience
- 15 March 1998
The present results indicate that inhibition byextracellular ATP of hippocampal synaptic transmission requires localized extracellular catabolism by ecto-nucleotidases and channeling of the generated adenosine to adenosines A1 receptors.
Caffeine and adenosine.
- J. Ribeiro, A. Sebastião
- Biology, MedicineJournal of Alzheimer's Disease
- 14 April 2010
Targeting approaches that involve ARs will enhance the possibilities to correct brain dysfunctions, via the universally consumed substance that is caffeine.
Adenosine receptors and the central nervous system.
- A. Sebastião, J. Ribeiro
- Biology, PsychologyHandbook of Experimental Pharmacology
- 2009
The time has come to determine the role of these receptors in neurological and psychiatric diseases and identify therapies that will alter the outcomes of these diseases, therefore providing a hopeful future for the patients who suffer from these diseases.
Evidence for functionally important adenosine A2a receptors in the rat hippocampus
- R. Cunha, B. Johansson, I. Ploeg, A. M. Sebastia˜o, J. Ribeiro, B. Fredholm
- BiologyBrain Research
- 27 June 1994
Preferential Release of ATP and Its Extracellular Catabolism as a Source of Adenosine upon High‐ but Not Low‐Frequency Stimulation of Rat Hippocampal Slices
- R. Cunha, E. Vizi, J. Ribeiro, A. Sebastião
- Biology, ChemistryJournal of Neurochemistry
- 1 November 1996
There is a simultaneous, but quantitatively different, release of ATP and adenosine from rat hippocampal slices stimulated at frequencies that can induce plasticity phenomena such as LTP (100 Hz) or LTD (5 Hz).
Adenosine A2A receptor facilitation of hippocampal synaptic transmission is dependent on tonic A1 receptor inhibition
- L. Lopes, R. Cunha, B. Kull, B. Fredholm, J. Ribeiro
- Biology, ChemistryNeuroscience
- 18 June 2002
Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset
- M. Rocha, Paula A. Pousinha, A. M. Correia, A. Sebastião, J. Ribeiro
- BiologyPLoS ONE
- 5 September 2013
Results are consistent with the hypothesis that the diaphragm of SOD1(G93A) mice is undergoing cycles of denervation/re-innervation supported by mixed neuromuscular junction populations and suggest that the ALS associated events start long before symptoms onset.
ATP as a presynaptic modulator.
- R. Cunha, J. Ribeiro
- BiologyLife Science
- 1 December 2000
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