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1,3-diethyl-8-phenylxanthine

Known as: 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-phenyl-, DEPX 
National Institutes of Health

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1 relation

Broader (1)

Xanthines

Papers overview

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Highly Cited
1995
Highly Cited
1995
Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography
Highly Cited
1995
Highly Cited
1995
Adenosine A2a and A2b receptors in cultured fetal chick heart cells. High- and low-affinity coupling to stimulation of myocyte contractility and cAMP accumulation.
Adenosine exerts pronounced biological effects in the heart cell. The role of multiple adenosine receptor subtypes in regulating… 
Highly Cited
1993
Highly Cited
1993
Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes.
Highly Cited
1990
Highly Cited
1990
The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8‐substituted xanthines
1 The ability of 1,3,8‐substituted xanthines to antagonize the inhibitory effects of adenosine receptor agonists on the amplitude… 
Highly Cited
1989
Highly Cited
1989
[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.
Characterization of the adenosine A2 receptor has been limited due to the lack of available ligands which have high affinity and… 
Highly Cited
1989
Highly Cited
1989
A permissive role of pertussis toxin substrate G-protein in P2-purinergic stimulation of phosphoinositide turnover and arachidonate release in FRTL-5 thyroid cells. Cooperative mechanism of signal…
Highly Cited
1989
Highly Cited
1989
Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain
1987
1987
Inhibition of radioligand binding to A1 adenosine receptors by Bay K8644 and nifedipine.
Highly Cited
1987
Highly Cited
1987
A1 and A2 adenosine receptors in rabbit cortical collecting tubule cells. Modulation of hormone-stimulated cAMP.
Adenosine analogs were used to investigate the cellular mechanisms by which adenosine may alter renal tubular function. Cultured… 
1986
1986
A Comparison Between the Adenosine Receptors Mediating Adenylate Cyclase Inhibition and Cardiac Depression in the Guinea Pig Heart
Summary: Stable analogues of adenosine were used to investigate the specificity of the receptors mediating its negative… 
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