Quantitation of uptake of bromine-77 in the human brain

@article{Crawley1984QuantitationOU,
  title={Quantitation of uptake of bromine-77 in the human brain},
  author={J. C. W. Crawley},
  journal={Clinical Physics and Physiological Measurement},
  year={1984},
  volume={5},
  pages={121-124},
  url={https://api.semanticscholar.org/CorpusID:120999336}
}
  • J. Crawley
  • Published 1 May 1984
  • Medicine, Physics
  • Clinical Physics and Physiological Measurement
A set of measurements on a realistic phantom has been used to obtain an empirical correction for measurements in vivo to display the dopamine receptors in the human brain using single photon emission tomography.
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3 Citations

3 Citations

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The preparation and use of [77Br]p-bromospiperone for clinical dopamine D2 receptor measurements.

5 References

Dopamine visualized in the basal ganglia of living man

It is shown here that L-3,4-dihydroxyphenylalanine (L-dopa) labelled in the 6-position with the positron-emitting radionuclide fluorine-18, localizes specifically in the dopaminergic pathways of the human brain where its turnover could be measured atraumatically by positron emission tomography.

Quantitative imaging using the Cleon emission tomography system: recent developments.

A revised method of correcting for attenuation has been investigated through experiments using discrete sources within a radioactive background, with marked improvement in results obtained using old and new attenuation corrections.

Quantitation in Positron Emission Computed Tomography: 5. Physical–Anatomical Effects

The effect of neuroanatomical structure size, shape, and position versus spatial tomographic resolution on quantitation in positron computed tomography was investigated and recommendations for error reduction and possible correction factors are provided.

A comparison of attenuation correction methods for quantitative single photon emission computed tomography.

The comparison assesses the importance of including a correction for attenuation as well as demonstrating how closely a simple geometric attenuation correction, applied to the filtered back-projection reconstruction method, approximates to a more accurate correction incorporated in the computation of line integrals during iterative reconstruction.

DOPAMINE RECEPTORS DISPLAYED IN LIVING HUMAN BRAIN WITH 77Br-p-BROMOSPIPERONE