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zopiclone

Known as: 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo(3,4-b)pyrazin-5-yl Ester, (+-)-Zopiclone, Zopiclona 
The racemic form of a nonbenzodiazepine, cyclopyrrolone with hypnotic and sedative activity and without significant anxiolytic activity. Although the… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (3)

Azabicyclo CompoundsHypnotics and SedativesPiperazines
EszopicloneZopiclone:MCnt:Pt:Hair:QnZopiclone:PrThr:Pt:Urine:OrdZopiclone:SCnc:Pt:Gast fld:Qn

Narrower (2)

ZopZopitan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Drug-facilitated sexual assault and analytical toxicology: the role of LC-MS/MS A case involving zolpidem.
Highly Cited
2005
Highly Cited
2005
Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of 26 benzodiazepines and metabolites, zolpidem and zopiclone, in blood, urine, and hair.
A liquid chromatography-tandem mass spectrometry method was developed for the simultaneous quantification of 26 benzodiazepines… 
Highly Cited
1999
Highly Cited
1999
Independent sleep EEG slow-wave and spindle band dynamics associated with 4 weeks of continuous application of short-half-life hypnotics in healthy subjects
Review
1998
Review
1998
Sleep in fibromyalgia patients: subjective and objective findings.
Highly Cited
1991
Highly Cited
1991
Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic
1991
1991
Misuse of Zopiclone and Convulsions during Withdrawal
It has been documented that benzodiazepines have the potential to cause dependence and withdrawal reactions, including… 
Highly Cited
1990
Highly Cited
1990
Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices
Highly Cited
1987
Highly Cited
1987
Dose-response effects of zopiclone on night sleep and on nighttime and daytime functioning.
Six normal volunteers, aged 20 to 39 years, underwent 2 adaptation nights and three sessions of 2 consecutive experimental nights… 
Highly Cited
1982
Highly Cited
1982
Pharmacological studies on zopiclone.
Zopiclone (RP 27 267) is an hypnotic with a chemical structure different from that of the benzodiazepines (BZD) or barbiturates… 
Highly Cited
1981
Highly Cited
1981
Do benzodiazepines bind at adenosine uptake sites in CNS?
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