Eszopiclone

Known as: (S)-Zopiclone, (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate, Esopiclone 
A nonbenzodiazepine, cyclopyrrolone and active stereoisomer of zopiclone with hypnotic and sedative activity and without significant anxiolytic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
0102020012017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Recent insights into sleep apnoea pathogenesis reveal that a low respiratory arousal threshold (awaken easily) is important for… (More)
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2011
2011
OBJECTIVE The development of novel strategies for the treatment of posttraumatic stress disorder (PTSD) represents a critical… (More)
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2009
2009
Eszopiclone (Lunesta; Sepracor, Marlborough, MA) and zolpidem [N,N,6-trimethyl-2-(4-methylphenyl)-imidazo(1,2-a)pyridine-3… (More)
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2008
2008
CONTEXT Insomnia and generalized anxiety disorder (GAD) are prevalent disorders that may coexist. OBJECTIVE To determine the… (More)
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2007
2007
OBJECTIVE To evaluate the effects of eszopiclone on measures of respiration and sleep using polysomnography in patients with mild… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Insomnia and major depressive disorder (MDD) can coexist. This study evaluated the effect of adding eszopiclone to… (More)
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2006
2006
OBJECTIVE To evaluate eszopiclone 3 mg for treatment of insomnia in perimenopausal and early postmenopausal women, as well as the… (More)
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2005
2005
BACKGROUND AND PURPOSE A double-blind placebo-controlled study of eszopiclone found significant, sustained improvement in sleep… (More)
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2004
2004
OBJECTIVE Eszopiclone is a new, single-isomer, non-benzodiazepine, cyclopyrrolone agent under investigation for the treatment of… (More)
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Highly Cited
2003
Highly Cited
2003
STUDY OBJECTIVES To determine the long-term efficacy of eszopiclone in patients with chronic insomnia. DESIGN Randomized… (More)
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