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Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents.
- T. Imanishi, A. Sawa, +4 authors S. Ueki
- Psychology, Medicine
- European journal of pharmacology
- 5 March 1997
It is suggested that rolipram might ameliorate the impairments of learning and memory by elevating cAMP levels. Expand
Analgesic effect of morphine glucuronides.
- K. Shimomura, O. Kamata, +4 authors H. Tsukamoto
- Medicine, Chemistry
- The Tohoku journal of experimental medicine
- 1 September 1971
The analgesic effect of morphine-6-glucuronide was 3 to 4 times as potent and approximately 2 times as long in duration as that of morphine when injected subcutaneously when injected intracerebrally in mice, but morphine-3-glUCuronide had no effect. Expand
Effects of 5-HT1A receptor agonists on the circadian rhythm of wheel-running activity in hamsters.
- K. Tominaga, S. Shibata, S. Ueki, S. Watanabe
- Chemistry, Medicine
- European journal of pharmacology
- 7 April 1992
Observations suggest that 5-HT1A receptors in the brain participate in the regulation of the circadian rhythm of wheel-running activity in hamsters. Expand
A new method for studying working memory by using the three-panel runway apparatus in rats.
This experimental procedure using the three-panel runway apparatus would be a useful method for studying working memory, and its memory deficit is involved at least in the dysfunction of the cholinergic system in the hippocampus. Expand
Behavioral effects of 2,5-dimethoxy-4-methylamphetamine (DOM) in rats and mice.
The characteristics of the behavioral effects of 2,5-dimethoxy-4-methylamphetamine (DOM or STP) were compared with those of mescaline and methamphetamine in rats and mice as well as in mice to study the effects of hyperactivity and biphasic changes. Expand
Optic nerve stimulation-induced increase of release of 3h-glutamate and 3h-aspartate but not 3h-gaba from the suprachiasmatic nucleus in slices of rat hypothalamus
The present result with previous electrophysiological observations strongly suggest that glutamate and/or aspartate are included in this retinohypothalamic termination, while GABA is included in intrinsic and/ or extrinsic neurons of the SCN, excluding the terminal of the retinodiazepine fibers. Expand
Influence of environmental light-dark cycle and enucleation on activity of suprachiasmatic neurons in slice preparations
The present results suggest that the dorsomedial part of the SCN is more important in regulation of the circadian rhythm of SCN neuronal activity than the ventrolateral. Expand
Cardiovascular changes induced by chemical stimulation of the amygdala in rats
The results suggest that the cholinergic system mediated by activation of muscarinic receptors in the amygdaloid complex may play a role in the control of cardiovascular and autonomic function. Expand
Effects of midbrain raphe stimulation and lesion on EEG activity in rats
The results suggest that the m-R plays a more important role than the d-R in regulating the hippocampal EEG activity, especially in inhibiting the appearance of high voltage synchronized waves in the hippocampus. Expand
Stimulatory Action of γ‐Aminobutyric Acid on Catecholamine Secretion from Bovine Adrenal Chromaffin Cells Measured by a Real‐Time Monitoring System
GA‐benzodiazepine receptor coupling can function in the secretion of CA from the adrenal chromaffin cells in a manner similar to that observed in the brain, suggesting the involvement of voltage‐sensitive Ca2+ channels in the mechanisms of the CA‐releasing action of GABA in these cells. Expand