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zomepirac

Known as: 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate dihydrate, 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid, Zomepiracum 
 
National Institutes of Health

Papers overview

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2012
2012
The glucuronide metabolites are important both for toxicology and for pharmacokinetics of many drugs and xenobiotics. Even though… Expand
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Highly Cited
1999
Highly Cited
1999
Pharmacokinetic studies demonstrated that the decrease in drug biotransformation in hepatic failure depends on the metabolic… Expand
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Highly Cited
1998
Highly Cited
1998
The effect on cytotoxicity of combining a range of clinically important non-steroidal anti-inflammatory drugs (NSAIDs) with a… Expand
Highly Cited
1998
Highly Cited
1998
Hepatotoxicity is one of the common side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). We investigated the… Expand
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Highly Cited
1993
Highly Cited
1993
A cDNA clone, designated UGT2B7 variant, encoding a 529-amino acid human liver microsomal uridine diphosphate… Expand
Highly Cited
1989
Highly Cited
1989
SYNOPSIS 
Highly Cited
1988
Highly Cited
1988
The formalin tonic pain test has recently been adapted for use in mice. We have observed two problems with this procedure. First… Expand
Highly Cited
1985
Highly Cited
1985
Information derived from pharmaceutical marketing databases on the use of 12 nonsteroidal antiinflammatory drugs in 1983 is… Expand
1980
1980
Zomepirac, an inhibitor of prostaglandin biosynthesis, was evaluated for analgesic activity in a number of pharmacological… Expand
1980
1980
THE activity of a new oral analgesic is initially established in man by comparing various dose levels of the test drug with a… Expand