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zomepirac

Known as: 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate dihydrate, 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid, Zomepiracum 
 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalTolmetin

Narrower (2)

ZomaxZomepirac sodium
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Quantification of Glucuronide Metabolites in Biological Matrices by LC-MS/MS
The glucuronide metabolites are important both for toxicology and for pharmacokinetics of many drugs and xenobiotics. Even though… Expand
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Highly Cited
1999
Highly Cited
1999
Glucuronidation of drugs by hepatic microsomes derived from healthy and cirrhotic human livers.
Pharmacokinetic studies demonstrated that the decrease in drug biotransformation in hepatic failure depends on the metabolic… Expand
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Highly Cited
1998
Highly Cited
1998
Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
The effect on cytotoxicity of combining a range of clinically important non-steroidal anti-inflammatory drugs (NSAIDs) with a… Expand
Highly Cited
1998
Highly Cited
1998
Structural requirements for the hepatotoxicity of nonsteroidal anti-inflammatory drugs in isolated rat hepatocytes.
Hepatotoxicity is one of the common side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). We investigated the… Expand
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Highly Cited
1993
Highly Cited
1993
Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.
A cDNA clone, designated UGT2B7 variant, encoding a 529-amino acid human liver microsomal uridine diphosphate… Expand
Highly Cited
1989
Highly Cited
1989
Drug‐Related Headache
SYNOPSIS 
Highly Cited
1988
Highly Cited
1988
Methodological refinements to the mouse paw formalin test. An animal model of tonic pain.
The formalin tonic pain test has recently been adapted for use in mice. We have observed two problems with this procedure. First… Expand
Highly Cited
1985
Highly Cited
1985
Utilization of nonsteroidal antiinflammatory drugs.
Information derived from pharmaceutical marketing databases on the use of 12 nonsteroidal antiinflammatory drugs in 1983 is… Expand
1980
1980
Evaluation of the Analgesic Properties of Zomepirac
Zomepirac, an inhibitor of prostaglandin biosynthesis, was evaluated for analgesic activity in a number of pharmacological… Expand
1980
1980
Efficacy of Zomepirac in Oral Surgical Pain
THE activity of a new oral analgesic is initially established in man by comparing various dose levels of the test drug with a… Expand
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