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zomepirac

Known as: 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate dihydrate, 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid, Zomepiracum 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalTolmetin

Narrower (2)

ZomaxZomepirac sodium
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
In vitro and in vivo studies on acyl-coenzyme A-dependent bioactivation of zomepirac in rats.
Zomepirac [ZP, 5-(chlorobenzoyl)-1,4-dimethylpyrrole-2-acetic acid] was withdrawn from the market because of unpredictable… 
2003
2003
Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.
Zomepirac (ZP), a nonsteroidal anti-inflammatory drug that was withdrawn from use, is metabolized to zomepirac-1-O-acyl… 
Highly Cited
1984
Highly Cited
1984
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.
1982
1982
Zomepirac sodium in the treatment of primary dysmenorrhea syndrome.
Zomepirac sodium was compared with placebo for relief of primary dysmenorrhea syndrome in a double-blind, crossover study of 47… 
1982
1982
Reversible nonoliguric acute renal failure associated with zomepirac therapy.
Zomepirac sodium (Zomax) is a nonsteroidal anti-inflammatory agent with analgesic properties which was recently released for… 
1980
1980
Evaluation of the Analgesic Properties of Zomepirac
Zomepirac, an inhibitor of prostaglandin biosynthesis, was evaluated for analgesic activity in a number of pharmacological… 
1980
1980
Efficacy of Zomepirac in Oral Surgical Pain
THE activity of a new oral analgesic is initially established in man by comparing various dose levels of the test drug with a… 
1980
1980
Zomepirac kinetics in healthy males
Kinetics of zomepirac, an oral, nonnarcotic analgesic, were studied in healthy males in 3 clinical experiments. In study A… 
1980
1980
Relative Analgesic Potency of Oral Zomepirac and Intramuscular Morphine in Cancer Patients with Postoperative Pain
A twin crossover assay of oral zomepirac and intramuscular morphine was completed in 159 cancer patients with postoperative pain… 
1980
1980
Double‐Blind Comparisons of Zomepirac and Oxycodone with APC in Cancer Pain
C HRONIC pain due to malignancy is often continuous and debilitating and eventually dominates the whole life style of the patient… 
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