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zomepirac

Known as: 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate dihydrate, 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid, Zomepiracum 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalTolmetin

Narrower (2)

ZomaxZomepirac sodium
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Highly Cited
2002
Highly Cited
2002
Differential binding mode of diverse cyclooxygenase inhibitors.
Highly Cited
1999
Highly Cited
1999
Glucuronidation of drugs by hepatic microsomes derived from healthy and cirrhotic human livers.
Pharmacokinetic studies demonstrated that the decrease in drug biotransformation in hepatic failure depends on the metabolic… 
Highly Cited
1998
Highly Cited
1998
Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
Highly Cited
1998
Highly Cited
1998
Structural requirements for the hepatotoxicity of nonsteroidal anti-inflammatory drugs in isolated rat hepatocytes.
Hepatotoxicity is one of the common side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). We investigated the… 
Highly Cited
1993
Highly Cited
1993
Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.
A cDNA clone, designated UGT2B7 variant, encoding a 529-amino acid human liver microsomal uridine diphosphate… 
Highly Cited
1989
Highly Cited
1989
Drug‐Related Headache
SYNOPSIS 
Highly Cited
1988
Highly Cited
1988
Methodological refinements to the mouse paw formalin test. An animal model of tonic pain.
Highly Cited
1984
Highly Cited
1984
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.
Highly Cited
1983
Highly Cited
1983
Soybean lipoxygenase inhibition by nonsteroidal antiinflammatory drugs.
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