FAQ

zomepirac

Known as: 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate dihydrate, 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid, Zomepiracum 
 

Topic mentions per year

Topic mentions per year

1979-2017
05101519792017

Related topics

Related topics

4 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalTolmetin

Narrower (1)

Zomax
Zomepirac sodium

Related mentions per year

Related mentions per year

1952-2019
1960198020002020
zomepirac
Anti-Inflammatory Agents, Non-Steroidal
Tolmetin
Zomepirac sodium
Zomax

Papers overview

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2006
2006
Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
Although zomepirac (ZP) and tolmetin (TM) induce anaphylactic reactions and form reactive acyl glucuronides, a direct link… (More)
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2003
2003
Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.
Zomepirac (ZP), a nonsteroidal anti-inflammatory drug that was withdrawn from use, is metabolized to zomepirac-1-O-acyl… (More)
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2001
2001
Dipeptidyl peptidase IV is a target for covalent adduct formation with the acyl glucuronide metabolite of the anti-inflammatory drug zomepirac.
The nonsteroidal anti-inflammatory drug zomepirac (ZP) is metabolised to a chemically reactive acyl glucuronide conjugate (ZAG… (More)
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1987
1987
The effect of indication on hypersensitivity reactions associated with zomepirac sodium and other nonsteroidal antiinflammatory drugs.
A large, computerized database derived from Medicaid claims was used to evaluate the risk of allergy and/or anaphylaxis… (More)
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1986
1986
Irreversible binding of zomepirac to plasma protein in vitro and in vivo.
Zomepirac is a nonsteroidal anti-inflammatory drug recently withdrawn from use because of an unexplained high incidence of… (More)
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1985
1985
Utilization of nonsteroidal antiinflammatory drugs.
Information derived from pharmaceutical marketing databases on the use of 12 nonsteroidal antiinflammatory drugs in 1983 is… (More)
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1983
1983
Abnormal glucuronidation of zomepirac in patients with cirrhosis of the liver.
The disposition of zomepirac was investigated in 18 patients with various liver diseases and in 10 healthy normal subjects in… (More)
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1983
1983
Ibuprofen, zomepirac, aspirin, and placebo in the relief of postepisiotomy pain.
Our purpose was to compare the analgesic efficacy of single oral doses of ibuprofen, zomepirac, aspirin, and placebo in severe… (More)
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1983
1983
Zomepirac-induced serum sickness. A report of two cases.
Two patients, after several weeks of zomepirac sodium use, experienced acute toxic eruption, fever, lymphadenopathy, arthralgias… (More)
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1982
1982
Liquid-chromatographic determination of zomepirac in serum and plasma.
We describe a determination of zomepirac concentration in plasma and serum by reversed-phase "high-performance" liquid… (More)
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