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Tolmetin

Known as: Tolmetinum, 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid, Tolmetina 
An arylalkanoic acid and non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory and antipyretic activities. Although the… 
National Institutes of Health

Related topics

Related topics

30 relations

Narrower (9)

4-fluoroketorolacAU 8001McN-2559Tolectin

Broader (4)

Analgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase InhibitorsPyrroles
Degenerative polyarthritisDrug AllergyIn BloodJuvenile arthritis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Hydrogen peroxide scavenging activity by non-steroidal anti-inflammatory drugs.
2001
2001
Determination of ketorolac in human plasma by reversed-phase high-performance liquid chromatography using solid-phase extraction and ultraviolet detection.
1999
1999
4-quinazolinones: synthesis and reduction of prostaglandin E2 production.
1999
1999
Effect of p‐Cyclodextrin Complexation on the Photochemical and Photosensitizing Properties of Tolmetin: A Steady‐State and Time‐Resolved Study
The effects of beta-cyclodextrin complexation on the photochemical and photosensitizing properties of tolmetin have been… 
1996
1996
In vitro displacement of phenytoin from protein binding by nonsteroidal antiinflammatory drugs tolmetin, ibuprofen, and naproxen in normal and uremic sera.
Displacement of phenytoin (90% bound to albumin) by other highly albumin-bound drugs like salicylate has been well documented… 
1992
1992
Separation of non-steroidal anti-inflammatory agents using supercritical fluid chromatography.
1985
1985
Tolmetin‐induced hemolysis
A case of drug‐associated immune hemolysis in a patient taking tolmetin for arthritic pain is described. Serologic tests showed… 
Highly Cited
1984
Highly Cited
1984
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.
Review
1982
Review
1982
Survey of antiinflammatory agents and related drugs as inhibitors of ovulation in the rabbit.
1978
1978
Protein binding of tolmetin
The protein binding of the new nonsteroidal anti‐inflammatory agent tolmetin to human serum albumin (HSA) and to the plasma of 8… 
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