Cyclooxygenase Inhibitors

Known as: Inhibitors, Cyclooxygenase, Clyclooxygenases Inhibitor, Inhibitors, Cyclo Oxygenase 
Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including… (More)
National Institutes of Health

Related topics

Related topics

48 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalEnzyme Inhibitors

Narrower (41)

AspirinDiclofenacDiflunisalEthonium
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In BloodProstaglandin Antagonistsaspects of radiation effectschemical synthesis
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Papers overview

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Review
2007
Review
2007
Anti-inflammatory and side effects of cyclooxygenase inhibitors.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs in inflammatory diseases, since they are effective… (More)
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Review
2004
Review
2004
Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.
Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most highly utilized classes of pharmaceutical agents in… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
 
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Review
2001
Review
2001
Cyclooxygenase-independent actions of cyclooxygenase inhibitors.
Several studies have demonstrated unequivocally that certain nonsteroidal anti-inflammatory drugs (NSAIDs) such as sodium… (More)
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Highly Cited
2001
Highly Cited
2001
Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities.
The antitumorigenic activity of nonsteroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase (COX) inhibitors, is well… (More)
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Highly Cited
2001
Highly Cited
2001
Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors.
BACKGROUND Cyclooxygenase-2 (COX-2) is thought to be linked to carcinogenesis; however, very little is known about its expression… (More)
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Highly Cited
1999
Highly Cited
1999
Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo.
Angiogenesis plays a key role in the development of malignant tumors. To clarify the roles of cyclooxygenase (COX) in malignant… (More)
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Highly Cited
1995
Highly Cited
1995
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
Prostaglandin endoperoxide synthase 2, also referred to as cyclooxygenase 2 (COX-2), is a key enzyme in the conversion of… (More)
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Highly Cited
1993
Highly Cited
1993
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Constitutive cyclooxygenase (COX-1; prostaglandin-endoperoxide synthase, EC 1.14.99.1) is present in cells under physiological… (More)
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Highly Cited
1993
Highly Cited
1993
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.
Murine prostaglandin endoperoxide (PGH) synthase-1 and PGH synthase-2 expressed in cos-1 cells were found to be differentially… (More)
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