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Cyclooxygenase Inhibitors

Known as: Inhibitors, Cyclooxygenase, Clyclooxygenases Inhibitor, Inhibitors, Cyclo Oxygenase 
Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including… 
National Institutes of Health

Related topics

Related topics

48 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalEnzyme Inhibitors

Narrower (41)

AspirinDiclofenacDiflunisalEthonium
In BloodProstaglandin Antagonistsaspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer.
PURPOSE Preclinical studies suggest that treatment with a selective cyclo-oxygenase-2 (COX-2) inhibitor may augment the antitumor… 
Highly Cited
1998
Highly Cited
1998
Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs.
Highly Cited
1997
Highly Cited
1997
Enhanced expression of cyclo-oxygenase isoenzyme 2 (COX-2) in asthmatic airways and its cellular distribution in aspirin-sensitive asthma.
BACKGROUND: There are two isoforms of cyclo-oxygenase (COX), namely COX-1 and COX-2. COX-1 is constitutively expressed in most… 
Highly Cited
1994
Highly Cited
1994
Cyclo‐oxygenase and nitric oxide synthase isoforms in rat carrageenin‐induced pleurisy
1 The profiles of cyclo‐oxygenase (COX) and nitric oxide synthase (NOS) isoforms were determined in the rat carrageenin‐induced… 
Highly Cited
1993
Highly Cited
1993
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1.
IL-1 is a pro-inflammatory cytokine which controls many features of the immune and inflammatory response. When injected into a… 
Highly Cited
1990
Highly Cited
1990
The oxidative modification of low-density lipoproteins by macrophages.
1. Mouse resident peritoneal macrophages in culture modified human 125I-labelled low-density lipoprotein (LDL) to a form that… 
Highly Cited
1989
Highly Cited
1989
Release of markedly increased quantities of prostaglandin D2 in vivo in humans following the administration of nicotinic acid.
Highly Cited
1986
Highly Cited
1986
A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia.
A pharmacological analysis was carried out to determine the possible role of aberrant calcium fluxes, vasoactive arachidonic acid… 
Highly Cited
1977
Highly Cited
1977
Prostaglandin endoperoxide E isomerase from bovine vesicular gland microsomes, a glutathione-requiring enzyme.
Highly Cited
1976
Highly Cited
1976
Altered platelet function in diabetes mellitus.
An increased sensitivity of platelets to aggregation from ADP and epinephrine is described in diabetics with or without vascular… 
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