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Cyclooxygenase Inhibitors

Known as: Inhibitors, Cyclooxygenase, Clyclooxygenases Inhibitor, Inhibitors, Cyclo Oxygenase 
Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including… Expand
National Institutes of Health

Related topics

Related topics

48 relations

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalEnzyme Inhibitors

Narrower (41)

AspirinDiclofenacDiflunisalEthonium
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In BloodProstaglandin Antagonistsaspects of radiation effectschemical synthesis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most highly utilized classes of pharmaceutical agents in… Expand
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Highly Cited
2002
Highly Cited
2002
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
 
Review
2001
Review
2001
Cyclooxygenase‐independent actions of cyclooxygenase inhibitors
Several studies have demonstrated unequivocally that certain nonsteroidal anti‐inflammatory drugs (NSAIDs) such as sodium… Expand
Highly Cited
2001
Highly Cited
2001
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
BACKGROUND Patients with arthritis and vascular disease may receive both low-dose aspirin and other nonsteroidal antiinflammatory… Expand
Highly Cited
1999
Highly Cited
1999
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis.
The beneficial actions of nonsteroid anti-inflammatory drugs (NSAID) can be associated with inhibition of cyclo-oxygenase (COX)-2… Expand
Highly Cited
1998
Highly Cited
1998
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs.
PURPOSE Both isoforms of cyclo-oxygenase, COX-1 and COX-2, are inhibited to varying degrees by all of the available nonsteroidal… Expand
Highly Cited
1993
Highly Cited
1993
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Constitutive cyclooxygenase (COX-1; prostaglandin-endoperoxide synthase, EC 1.14.99.1) is present in cells under physiological… Expand
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Highly Cited
1993
Highly Cited
1993
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.
Murine prostaglandin endoperoxide (PGH) synthase-1 and PGH synthase-2 expressed in cos-1 cells were found to be differentially… Expand
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Review
1989
Review
1989
Interleukin-1 and its biologically related cytokines.
Publisher Summary Interleukin-1 (IL-1) and tumor necrosis factor (TNF) participate in self-augmentation induction mechanisms… Expand
Highly Cited
1988
Highly Cited
1988
Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.
Endothelin releases prostacyclin and thromboxane A2 from guinea pig or rat isolated lungs and endothelium-derived relaxing factor… Expand
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