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Diflunisal
Known as:
5-(2,4-Difluorophenyl)salicylic acid
, 2',4'-Difluoro-4-hydroxy-(1,1'-biphenyl)-3-carboxylic Acid
, Diflunisalum
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A difluorophenyl derivate of salicylic acid and a nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic and anti-inflammatory…
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National Institutes of Health
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Related topics
Related topics
24 relations
Narrower (7)
3-hydroxydiflunisal
Dolobid
MK-647
O-acetyldiflunisal
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Broader (2)
Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase Inhibitors
Degenerative polyarthritis
Drug Allergy
Gastrointestinal Hemorrhage
In Blood
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The utilization of drug–polymer interactions for improving the chemical stability of hot‐melt extruded solid dispersions
Zhefei Guo
,
Ming Lu
,
+4 authors
Chuanbin Wu
The Journal of pharmacy and pharmacology
2014
Corpus ID: 206137606
Interactions between drugs and polymers were utilized to lower the processing temperature of hot‐melt extrusion (HME), and thus…
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Highly Cited
2008
Highly Cited
2008
Chemometric assisted solid-phase microextraction for the determination of anti-inflammatory and antiepileptic drugs in river water by liquid chromatography-diode array detection.
L. Vera‐Candioti
,
M. D. G. García
,
M. Galera
,
H. Goicoechea
Journal of Chromatography A
2008
Corpus ID: 206691506
2005
2005
Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
Qiao-Hong Chen
,
P. Rao
,
E. Knaus
Bioorganic & Medicinal Chemistry
2005
Corpus ID: 21362841
Highly Cited
2004
Highly Cited
2004
Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.
M. R. Almeida
,
B. Macedo
,
+5 authors
M. Saraiva
Biochemical Journal
2004
Corpus ID: 15625062
In familial amyloidotic polyneuropathy, TTR (transthyretin) variants are deposited as amyloid fibrils. It is thought that this…
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1994
1994
Comparative cytotoxicity of non-steroidal anti-inflammatory drugs in primary cultures of rat hepatocytes.
M. Jurima‐Romet
,
K. Crawford
,
H. S. Huang
Toxicology in Vitro
1994
Corpus ID: 12326366
1989
1989
Rapid high-performance liquid chromatographic methods for the determination of overdose concentrations of some non-steroidal anti-inflammatory drugs in plasma or serum.
P. Streete
Journal of Chromatography A
1989
Corpus ID: 13322420
1989
1989
Pathways of hepatic glycogen formation in humans following ingestion of a glucose load in the fed state.
I. Magnusson
,
V. Chandramouli
,
W. Schumann
,
K. Kumaran
,
J. Wahren
,
B. Landau
Metabolism: Clinical and Experimental
1989
Corpus ID: 23495121
Highly Cited
1985
Highly Cited
1985
An open study of diflunisal, conservative and manipulative therapy in the management of acute mechanical low back pain.
Waterworth Rf
,
Hunter Ia
1985
Corpus ID: 77015505
Abstract One hundred and twelve patients with acute mechanical low back pain were randomly divided into three treatment groups…
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Highly Cited
1983
Highly Cited
1983
Antiinflammatory drugs: protection of a bacterial virus as an in vitro biological measure of free radical activity.
K. Hiller
,
P. Hodd
,
R. Willson
Chemico-Biological Interactions
1983
Corpus ID: 27788070
Highly Cited
1977
Highly Cited
1977
Pharmacology and toxicology of diflunisal.
C. A. Stone
,
C. G. Van Arman
,
+10 authors
S. E. Mckinney
British Journal of Clinical Pharmacology
1977
Corpus ID: 34629316
Abstract 1 Diflunisal, a new salicylate, possesses anti-inflammatory, analgesic and antipyretic activity. It was found to be…
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