Zomepirac sodium

OBJECTIVE To examine changes in the prescribing of analgesics after the market entry and subsequent withdrawal of zomepirac… Expand

A large, computerized database derived from Medicaid claims was used to evaluate the risk of allergy and/or anaphylaxis… Expand

The relative analgesic efficacy and safety of single oral doses of 50 and 100 mg of flurbiprofen (Ansaid, Upjohn) were compared… Expand

Ibuprofen (Motrin, Upjohn) was evaluated in five studies using the Dental Pain Model, which is representative of most acute… Expand

The nonsteroidal anti-inflammatory drugs are widely used in the United States and are a frequent cause of cutaneous reactions… Expand

Our purpose was to compare the analgesic efficacy of single oral doses of ibuprofen, zomepirac, aspirin, and placebo in severe… Expand

Abstract: Five healthy male human subjects were administered 200 mg oral solution doses of zomepirac‐14C sodium. Plasma and urine… Expand

Abstract: In a single‐dose, double‐blind crossover study in 40 patients with chronic pain due to advanced cancer, zomepirac… Expand

Zomepirac sodium (ZS) is an orally active, nonnarcotic, analgesic agent. The disposition and pharmacokinetics of zomepirac (Z… Expand

5-(4-Chlorobenzoyl)-4-(hydroxymethyl)-1-methyl-1H-pyrrole-2-acetic acid (2), the major oxidative metabolite of zomepirac (1), was… Expand