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verlukast

Known as: (3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)((3-dimethylamino-3-oxopropyl)thio)methyl)thiopropanoic acid, L-668019, L-668,019 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Bronchodilator AgentsLeukotriene AntagonistsPropionatesQuinolines

Narrower (3)

L 660,711MK 0571MK 0679

Papers overview

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1999
1999
Effects of loratadine and verlukast on ovalbumin-induced contraction in vitro and eosinophil infiltration in vivo in the airways of guinea-pigs
1995
1995
Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile.
Verlukast (MK-0679) is a potent leukotriene D4 antagonist that was under development for the treatment of bronchial asthma. A… 
1994
1994
Robotic sample preparation and high-performance liquid chromatographic analysis of verlukast in human plasma.
1993
1993
CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans.
It has previously been shown that Verlukast is converted to Verlukast dihydrodiol in microsomes from beta-naphthoflavone (BNF… 
1993
1993
Characterization of verlukast metabolites arising from an epoxide intermediate produced with hepatic microsomes from beta-naphthoflavone-treated rodents (P-4501A1).
Verlukast, (R)3-((((3-(2-(7-chloroquinolin-2-yl)-(E)-ethenyl)phenyl)-3- dimethylamino-3-oxopropylthio)methyl)thio)-propionic acid… 
1993
1993
Oral pharmacokinetics and food interaction of the leukotriene D4 receptor antagonist verlukast.
The influence of dose and food on the pharmacokinetic profile of orally administered verlukast, a leukotriene D4 receptor… 
1992
1992
Enantioselective induction of peroxisomal proliferation in CD-1 mice by leukotriene antagonists.
1992
1992
In vitro and in vivo biotransformations of the potent leukotriene D4 antagonist verlukast in the rat.
Verlukast, (S)3-((((3-(2-(7-chloroquinolin-2-yl)-(E)-ethenyl)phenyl)- 3-dimethylamino-3-oxopropylthio)methyl)thio)propionic acid… 
1992
1992
Bronchodilator properties of an inhaled leukotriene D4 antagonist (verlukast--MK-0679) in asthmatic patients.
1991
1991
Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571.
Verlukast (MK-679) (3-[(3-(2-(7-chloro-2-quinolinyl)-(E)-ethenyl)phenyl)[3-(dimethylamino)- 3- oxopropyl)thio)methyl)-thio… 
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