Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,179,278 papers from all fields of science
Search
Sign In
Create Free Account
MK 0679
Known as:
MK-0679
, MK-679
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
Broader (1)
verlukast
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Effect of selective cysteinyl leukotriene receptor antagonists on airway inflammation and matrix metalloproteinase expression in a mouse asthma model.
Chia-Hsiu Hsu
,
Chun-Ming Hu
,
+5 authors
K. Lue
Pediatrics and neonatology
2012
Corpus ID: 32829863
Highly Cited
2000
Highly Cited
2000
Priming of alveolar macrophages by leukotriene D(4): potentiation of inflammation.
G. Ménard
,
E. Bissonnette
American journal of respiratory cell and…
2000
Corpus ID: 37938753
Cysteinyl leukotrienes (LTs), including LTC(4), LTD(4), and LTE(4), are well known to induce bronchoconstriction and increase…
Expand
Review
1997
Review
1997
Leukotrienes in the pathogenesis of asthma.
P. O'Byrne
Chest
1997
Corpus ID: 27390855
Asthma is a chronic inflammatory disease that is associated with widespread but variable airflow obstruction. The mechanisms that…
Expand
1996
1996
Induction of hyperresponsiveness in human airway tiss by neutrophils — mechanism of action
S. Anticevich
,
J. Hughes
,
J. Black
,
C. Armour
Clinical and experimental allergy : journal of…
1996
Corpus ID: 21240428
Background The two main features of asthtna are bronchial hyperresponsiveness and inflammation. The inflammatory response in…
Expand
1996
1996
Drug substance manufacture process control: application of flow injection analysis and HPLC for monitoring an enantiospecific synthesis.
K. Chong
,
T. Loughlin
,
+6 authors
G. Bicker
Journal of pharmaceutical and biomedical analysis
1996
Corpus ID: 39110277
Highly Cited
1993
Highly Cited
1993
The leukotriene-receptor antagonist MK-0679 blocks airway obstruction induced by inhaled lysine-aspirin in aspirin-sensitive asthmatics.
B. Dahlén
,
M. Kumlin
,
+5 authors
S. Dahlén
The European respiratory journal
1993
Corpus ID: 7185944
Drugs which block the action or formation of the cysteinyl leukotrienes (LTC4, LTD4 and LTE4) inhibit asthmatic responses evoked…
Expand
Highly Cited
1993
Highly Cited
1993
Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects.
B. Dahlén
,
D. Margolskee
,
O. Zetterström
,
S. Dahlén
Thorax
1993
Corpus ID: 25024214
BACKGROUND--The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) have been shown to mediate airway obstruction evoked by several…
Expand
1993
1993
Acute bronchodilation with an intravenously administered leukotriene D4 antagonist, MK-679.
N. Impens
,
T. Reiss
,
+7 authors
A. Dupont
The American review of respiratory disease
1993
Corpus ID: 25234698
Descriptive studies suggest an association between the release of the cysteinyl leukotrienes and clinical asthma. To help clarify…
Expand
1992
1992
Bronchodilator properties of an inhaled leukotriene D4 antagonist (verlukast--MK-0679) in asthmatic patients.
J. Lammers
,
P. V. Van Daele
,
+4 authors
B. Friedman
Pulmonary pharmacology
1992
Corpus ID: 46247129
1991
1991
Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571.
T. Jones
,
R. Zamboni
,
+7 authors
P. Masson
Canadian journal of physiology and pharmacology
1991
Corpus ID: 23321154
Verlukast (MK-679) (3-[(3-(2-(7-chloro-2-quinolinyl)-(E)-ethenyl)phenyl)[3-(dimethylamino)- 3- oxopropyl)thio)methyl)-thio…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE