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MK 0679

Known as: MK-0679, MK-679 
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Cysteinyl leukotrienes (LTs), including LTC(4), LTD(4), and LTE(4), are well known to induce bronchoconstriction and increase… 
Review
1997
Review
1997
Asthma is a chronic inflammatory disease that is associated with widespread but variable airflow obstruction. The mechanisms that… 
1996
1996
Background The two main features of asthtna are bronchial hyperresponsiveness and inflammation. The inflammatory response in… 
Highly Cited
1993
Highly Cited
1993
Drugs which block the action or formation of the cysteinyl leukotrienes (LTC4, LTD4 and LTE4) inhibit asthmatic responses evoked… 
Highly Cited
1993
Highly Cited
1993
BACKGROUND--The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) have been shown to mediate airway obstruction evoked by several… 
1993
1993
Descriptive studies suggest an association between the release of the cysteinyl leukotrienes and clinical asthma. To help clarify… 
1991
1991
Verlukast (MK-679) (3-[(3-(2-(7-chloro-2-quinolinyl)-(E)-ethenyl)phenyl)[3-(dimethylamino)- 3- oxopropyl)thio)methyl)-thio…