Leukotriene Antagonists

Known as: inhibitors leukotriene receptor, Leukotriene Receptor Antagonists, leukotriene antagonist 
A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
05010015019792017

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Cysteinyl leukotrienes (CysLTs) contribute to asthma pathogenesis, in part through cysteinyl leukotriene receptor 1… (More)
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Highly Cited
2007
Highly Cited
2007
RATIONALE One-quarter to one-third of individuals with asthma smoke, which may affect response to therapy and contribute to poor… (More)
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Highly Cited
2007
Highly Cited
2007
Resolvin E1 (RvE1) is a potent anti-inflammatory and proresolving mediator derived from omega-3 eicosapentaenoic acid generated… (More)
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Highly Cited
2002
Highly Cited
2002
Leukotriene antagonists block the proinflammatory actions of leukotrienes (LT) and have been introduced as new treatments for… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The greatest prevalence of asthma is in preschool children; however, the clinical utility of asthma therapy for this… (More)
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Highly Cited
1999
Highly Cited
1999
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To determine the ability of montelukast, a leukotriene receptor antagonist, to allow tapering of inhaled… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVES To determine the clinical effect of oral montelukast sodium, a leukotriene receptor antagonist, in asthmatic patients… (More)
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Highly Cited
1996
Highly Cited
1996
Inflammation is a local immune response to 'foreign' molecules, infection and injury. Leukotriene B4, a potent chemotactic agent… (More)
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Highly Cited
1980
Highly Cited
1980
Arachidonic acid is metabolised either by cyclooxygenases to produce prostaglandins and thromboxanes or by lipoxygenases to… (More)
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