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Leukotriene Antagonists

Known as: inhibitors leukotriene receptor, Leukotriene Receptor Antagonists, leukotriene antagonist 
A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
National Institutes of Health

Related topics

Related topics

20 relations

Broader (1)

Anti-Asthmatic Agents

Narrower (14)

FPL 55712L 648051L 649923LY 171883
In BloodLeukotriene Receptor Antagonist [EPC]aspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells.
We have recently shown that leukotriene D(4) (LTD(4)) increases cell survival in intestinal epithelial cells. Here we report and… 
Highly Cited
2001
Highly Cited
2001
Identification of an Amino Acid Residue in Multidrug Resistance Protein 1 Critical for Conferring Resistance to Anthracyclines*
Murine multidrug resistance protein 1 (mrp1), unlike human MRP1, does not confer resistance to anthracyclines. Previously, we… 
Highly Cited
1996
Highly Cited
1996
Synthesis and pharmacological activity of triazole derivatives inhibiting eosinophilia.
In order to develop novel antiasthmatic agents based on a new mechanism of action, a series of 3-substituted 5-amino-1… 
Highly Cited
1991
Highly Cited
1991
Cloning of a phospholipase A2-activating protein.
Recently we have described the isolation and biochemical characterization of a phospholipase A2-activating protein (PLAP). We… 
Review
1989
Review
1989
The signal transduction system of the leukotriene D4 receptor.
Highly Cited
1986
Highly Cited
1986
Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia.
Vasoactive arachidonic acid metabolites are postulated to play a role in the pathogenesis of cerebral ischemia. In order to… 
Highly Cited
1985
Highly Cited
1985
Studies of leukotriene B4-specific binding and function in rat polymorphonuclear leukocytes: absence of a chemotactic response.
Rat PMN isolated from peripheral blood show a small amount of high-affinity (specific) binding of [3H]-LTB4 at nanomolar… 
Highly Cited
1983
Highly Cited
1983
The myeloperoxidase-dependent metabolism of leukotrienes C4, D4, and E4 to 6-trans-leukotriene B4 diastereoisomers and the subclass-specific S-diastereoisomeric sulfoxides.
Highly Cited
1981
Highly Cited
1981
Metabolism of leukotriene D by porcine kidney.
Highly Cited
1981
Highly Cited
1981
Tetraene and pentaene leukotrienes: selective production from murine mastocytoma cells after dietary manipulation.
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