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FPL 55712

Known as: 7-((3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxyl))-4-oxo-8-propyl-4H-chromene-2-carboxy late, sodium salt, FPL-55712 
 
National Institutes of Health

Papers overview

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1987
1987
1 The pressor and vascular permeability effects of leukotrienes B4 (LTB4), C4 and D4 were investigated in conscious unrestrained… Expand
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1985
1985
We investigated the effects of BW 755C, an inhibitor of both the cyclooxygenase and lipoxygenase pathways of arachidonic acid… Expand
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1983
1983
Arachidonic acid, metabolized by the enzyme contained in the cell-free homogenate of rat basophilic leukemia (RBL-1) cells… Expand
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Highly Cited
1982
Highly Cited
1982
Allergic pulmonary reactions in vivo lead to airway constriction and mucous secretion, whereas in vitro lung anaphylaxis lead to… Expand
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Highly Cited
1982
Highly Cited
1982
1 Leukotriene C4 (LTC4), LTD4, slow‐reacting substance of anaphylaxis (SRS‐A) (from guinea‐pig lung), bradykinin (Bk) and… Expand
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Highly Cited
1981
Highly Cited
1981
Abstract The possible importance of leukotrienes (LTs) as mediators of bronchoconstriction was examined in two normal volunteers… Expand
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Highly Cited
1981
Highly Cited
1981
The biological actions of pure slow-reacting substance of anaphylaxis (SRS-A) from guinea-pig lung, pure slow-reacting substance… Expand
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Highly Cited
1979
Highly Cited
1979
Murine mastocytoma cells treated with calcium ionophore A23187 produced a slow-reacting substance (SRS) that caused guinea pig… Expand
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1977
1977
FPL 55712, previously reported to be a selective antagonist of SRS-A on the guinea-pig ileum, has now been shown to be similarly… Expand
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Highly Cited
1973
Highly Cited
1973
IN the guinea-pig, anaphylaxis in the lung leads to the release of slow reacting substance of anaphylaxis (SRS-A) and histamine… Expand
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