FPL 55712

Known as: 7-((3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxyl))-4-oxo-8-propyl-4H-chromene-2-carboxy late, sodium salt, FPL-55712 
 
National Institutes of Health

Papers overview

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1992
1992
Exposure of rats to ozone (O3) produces an increase in airway permeability and a concomitant influx of polymorphonuclear… (More)
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1985
1985
We have previously shown that FPL 55712, a specific leukotriene receptor antagonist, potentiates estrogen induced uterine… (More)
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1984
1984
FPL 55712 was investigated by the aerosol route of administration for efficacy at protecting against leukotriene-induced… (More)
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1983
1983
Intracoronary leukotriene D4, 0.1-3.0 micrograms (0.2-6.0 nmol), produced dose-dependent decreases in coronary flow of… (More)
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1983
1983
Arachidonic acid, metabolized by the enzyme contained in the cell-free homogenate of rat basophilic leukemia (RBL-1) cells… (More)
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1983
1983
Leukotrienes D4 greater than C4 greater than E4 greater than F4 produced qualitatively similar contractions of guinea-pig… (More)
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Highly Cited
1982
Highly Cited
1982
Allergic pulmonary reactions in vivo lead to airway constriction and mucous secretion, whereas in vitro lung anaphylaxis lead to… (More)
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1981
1981
The activity of the SRS-A antagonist FPL 55712 against histamine, carbachol and ion-induced contraction of isolated airway smooth… (More)
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Highly Cited
1979
Highly Cited
1979
Murine mastocytoma cells treated with calcium ionophore A23187 produced a slow-reacting substance (SRS) that caused guinea pig… (More)
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1977
1977
FPL 55712, previously reported to be a selective antagonist of SRS-A on the guinea-pig ileum, has now been shown to be similarly… (More)
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