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urea cycle

Known as: cycle urea, urea biosynthetic process, ornithine cycle 
The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction… 
National Institutes of Health

Related topics

Related topics

4 relations
Krebs Henseleit cycleReye SyndromeUreaamino acid metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
New indications and controversies in arginine therapy.
Highly Cited
1997
Highly Cited
1997
The Glucocorticoid-responsive Gene Cascade
The gene for liver-type arginase, an ornithine cycle enzyme, is induced by glucocorticoids in a delayed secondary manner. An… 
Highly Cited
1994
Highly Cited
1994
Argininosuccinate synthetase mRNA and activity are induced by immunostimulants in vascular smooth muscle. Role in the regeneration or arginine for nitric oxide synthesis.
Highly Cited
1992
Highly Cited
1992
Immunohistochemical localization of argininosuccinate synthetase in the rat brain in relation to nitric oxide synthase-containing neurons
Highly Cited
1991
Highly Cited
1991
Citrulline in the rat brain: Immunohistochemistry and coexistence with NADPH-diaphorase
Highly Cited
1988
Highly Cited
1988
Regulation of messenger ribonucleic acid levels for five urea cycle enzymes in cultured rat hepatocytes. Requirements for cyclic adenosine monophosphate, glucocorticoids, and ongoing protein…
In adult rat liver, amounts of the urea cycle enzymes are regulated by diet, glucocorticoids, and cAMP. Rat hepatocytes cultured… 
Highly Cited
1973
Highly Cited
1973
Transport of ornithine and citrulline across the mitochondrial membrane.
Highly Cited
1973
Highly Cited
1973
Some regulatory mechanisms in the synthesis of urea in the mammalian liver.
Review
1972
Review
1972
Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.
Highly Cited
1956
Highly Cited
1956
A clinical study of the effect of arginine on blood ammonia.
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