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Lessons Learned From More Than 1,000 Pancreas Transplants at a Single Institution
ObjectiveTo determine outcome in diabetic pancreas transplant recipients according to risk factors and the surgical techniques and immunosuppressive protocols that evolved during a 33-year period atExpand
Risk factors for chronic rejection in renal allograft recipients.
Chronic rejection is a major barrier to long-term renal allograft survival. Cyclosporine, though effective at reducing graft loss to acute rejection, has had little impact on the incidence of chronicExpand
Vascular graft thrombosis after pancreatic transplantation: univariate and multivariate operative and nonoperative risk factor analysis.
BACKGROUND Vascular thrombosis is still the leading cause of nonimmunologic, technical pancreatic transplant graft failures. The paucity of published data--coupled with our large institutionalExpand
20 years or more of follow-up of living kidney donors
The perioperative and long-term risks for living kidney donors are of concern. We have studied donors at the University of Minnesota 20 years or more (mean 23.7) after donation by comparing renalExpand
Autologous Islet Transplantation to Prevent Diabetes After Pancreatic Resection
Background Extensive pancreatic resection for small‐duct chronic pancreatitis is often required for pain relief, but the risk of diabetes is a major deterrent. Objective Incidence of pain relief,Expand
Employment patterns after successful kidney transplantation.
We studied 822 kidney transplant recipients followed 1-9 years to determine the dynamics of their entering and leaving the work force. Multivariate analysis revealed that not being diabetic and thatExpand
Quantitative glomerular morphology of the normal human kidney.
We determined glomerular basement membrane (GBM) width (as the harmonic mean) and relative volumes of the glomerular mesangium and of its cellular and matrix components in 59 male (73%Expand
Effect of initial slow graft function on renal allograft rejection and survival.
Cadaver renal allografts with immediate excellent function have good long-term outcomes, while grafts with delayed function have been associated with an increased incidence of acute rejection (AR)Expand
Five preventable causes of kidney graft loss in the 1990s: a single-center analysis.
BACKGROUND Despite improvements in immunosuppressive protocols and patient care, kidney allografts continue to fail. We studied causes of graft loss for primary kidney transplants in the 1990s toExpand
Effects of intrasplenic injection of hepatocytes, hepatocyte fragments and hepatocyte culture supernatants on D-galactosamine-induced liver failure in rats.
Intraperitoneal injection of 0.5 g/kg D-galactosamine results in 95% lethal acute acute liver failure in male Fisher 344 rats. Intrasplenic injection of viable syngeneic hepatocytes 20-28 h afterExpand