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urapidil

Known as: 6-((3-(4- (2-methoxyphenyl)-1-piperazinyl)propyl)amino)- 1,3-dimethyl-2,4(1H,3H)-pyrimidinedione, 6-(3-(4-(o-methoxyphenyl)-1-piperazinyl)propylamino)-1,3-dimethyluracil 
 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (5)

Adrenergic alpha-1 Receptor AntagonistsAntihypertensive AgentsPiperazinesSerotonin Agonists
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Narrower (2)

Ebrantilurapidil monohydrochloride

Papers overview

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Highly Cited
2011
Highly Cited
2011
Thrombolysis treatment for acute ischaemic stroke in a patient on treatment with dabigatran.
Thrombolysis treatment for acute ischaemic stroke in a patient on treatment with dabigatran - 
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Highly Cited
2004
Highly Cited
2004
Combination of a cholinergic drug and an α‐blocker is more effective than monotherapy for the treatment of voiding difficulty in patients with underactive detrusor
Aim:  The aim of the present study was to compare the effectiveness of a cholinergic drug, an α‐blocker and combinations of the… Expand
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Highly Cited
2004
Highly Cited
2004
Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for α1-adrenoceptor binding sites
SummaryThe mechanism responsible for the antihypertensive effect of urapidil is not yet completely understood. Its vasodilator… Expand
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Highly Cited
2001
Highly Cited
2001
Clonidine decreases intraoperative bleeding in middle ear microsurgery
Background: The antihypertensive drug clonidine is a centrally acting α2 agonist useful as a premedicant because of its sedative… Expand
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Highly Cited
2001
Highly Cited
2001
A Comparison Between Meperidine, Clonidine and Urapidil in the Treatment of Postanesthetic Shivering
Postanesthetic shivering can be treated with many types of drugs. We compared the effects of meperidine, clonidine, and urapidil… Expand
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Highly Cited
2000
Highly Cited
2000
A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering.
UNLABELLED This placebo-controlled study was performed to evaluate the efficacy of urapidil compared with clonidine and… Expand
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Highly Cited
1999
Highly Cited
1999
Modulation of Long-Term Synaptic Depression in Visual Cortex by Acetylcholine and Norepinephrine
In a slice preparation of rat visual cortex, we discovered that paired-pulse stimulation (PPS) elicits a form of homosynaptic… Expand
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Highly Cited
1999
Highly Cited
1999
A role for norepinephrine in stress-induced cognitive deficits: α-1-adrenoceptor mediation in the prefrontal cortex
BACKGROUND Stress exacerbates many neuropsychiatric disorders associated with prefrontal cortical (PFC) dysfunction. Stress also… Expand
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Highly Cited
1994
Highly Cited
1994
COMPARATIVE STUDY ON α1‐ADRENOCEPTOR ANTAGONIST BINDING IN HUMAN PROSTATE AND AORTA
1. Specific binding of [3H]‐prazosin in prostatic and aortic membranes of humans was saturable and of high affinity (prostate… Expand
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Highly Cited
1989
Highly Cited
1989
Subclassification of α1‐adrenoceptor recognition sites by urapidil derivatives and other selective antagonists
1 The affinities of urapidil derivatives and other antagonists for α1‐adrenoceptors labelled by [3H]‐prazosin were determined on… Expand
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