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tyrosinase peptide

Known as: TYRP, Tyrosinase Peptides 
One of a number of recombinant peptides consisting of amino acid residues of the enzyme tyrosinase, a protein frequently expressed by melanoma cells… 
National Institutes of Health

Related topics

Related topics

11 relations
Antigen SensitizationCRL 1005/gp100 antigen/Montanide ISA-51/tyrosinase peptideCytotoxic T-LymphocytesT-Cell Activation

Papers overview

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Highly Cited
2013
Highly Cited
2013
A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo
T cell cytolytic activity targeting epidermal melanocyte is shown to cause progressive depigmentation and autoimmune vitiligo… 
Highly Cited
2007
Highly Cited
2007
Cross-reaction between tyrosinase peptides and cytomegalovirus antigen by T cells from patients with Vogt-Koyanagi-Harada disease
AbstractAim To determine whether T lymphocytes of patients with Vogt–Koyanagi–Harada (VKH) disease cross-react with peptides of… 
Highly Cited
2003
Highly Cited
2003
Cytotoxic T lymphocyte reactivity to gp100, MelanA/MART-1, and tyrosinase, in HLA-A2-positive vitiligo patients.
Vitiligo is a common depigmentation disorder thought to result from autoimmune destruction of melanocytes. Recent studies suggest… 
Highly Cited
2001
Highly Cited
2001
The role of heat shock protein (hsp70) in dendritic cell maturation: Hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors
Members of the heat shock protein (hsp70) family are either constitutively expressed (hsc70) or can be induced by hyperthermic… 
Highly Cited
2000
Highly Cited
2000
Phase 2 Trial of Vaccination With Tyrosinase Peptides and Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Metastatic Melanoma
This phase II study was performed to determine the induction of a specific T-cell response, the clinical response rate, and… 
Highly Cited
1999
Highly Cited
1999
Inducing autoimmune disease to treat cancer.
For many years, visions for development of successful immunotherapy of cancer revolved around the induction of immune responses… 
Highly Cited
1999
Highly Cited
1999
Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.
The human tyrosinase gene codes for two distinct antigens that are recognized by HLA-A*0201-restricted CTLs. For one of them… 
Highly Cited
1996
Highly Cited
1996
Detection and quantification of blood-derived CD8+ T lymphocytes secreting tumor necrosis factor alpha in response to HLA-A2.1-binding melanoma and viral peptide antigens.
Highly Cited
1994
Highly Cited
1994
Two tyrosinase nonapeptides recognized on HLA‐A2 melanomas by autologous cytolytic T lymphocytes
A number of cytolytic T lymphocyte (CTL) clones derived from several melanoma patients have been found to recognize a majority of… 
Highly Cited
1994
Highly Cited
1994
Substrate specificity of protein kinase CK2.
Unlike most Ser/Thr protein kinases which recognize phosphoacceptor sites specified by basic residues, protein kinase CK2 is… 
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