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tyrosinase peptide

Known as: TYRP, Tyrosinase Peptides 
One of a number of recombinant peptides consisting of amino acid residues of the enzyme tyrosinase, a protein frequently expressed by melanoma cells… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
The tyrosine decarboxylase operon of Lactobacillus brevis IOEB9809 contains, adjacent to the tyrosine decarboxylase gene, a gene… Expand
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Highly Cited
2003
Highly Cited
2003
Vitiligo is a common depigmentation disorder thought to result from autoimmune destruction of melanocytes. Recent studies suggest… Expand
Highly Cited
2003
Highly Cited
2003
PURPOSE To determine clinical and immunologic responses to a multipeptide melanoma vaccine regimen, a randomized phase II trial… Expand
Highly Cited
2002
Highly Cited
2002
Our study demonstrates that tumor-derived heat shock protein (HSP)70 chaperones a tyrosinase peptide and mediates its transfer to… Expand
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Highly Cited
2001
Highly Cited
2001
Members of the heat shock protein (hsp70) family are either constitutively expressed (hsc70) or can be induced by hyperthermic… Expand
Highly Cited
2000
Highly Cited
2000
This phase II study was performed to determine the induction of a specific T-cell response, the clinical response rate, and… Expand
Highly Cited
1999
Highly Cited
1999
  • D. Pardoll
  • Proceedings of the National Academy of Sciences…
  • 1999
  • Corpus ID: 40474100
For many years, visions for development of successful immunotherapy of cancer revolved around the induction of immune responses… Expand
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Highly Cited
1997
Highly Cited
1997
The loss of tyrosinase, the key enzyme in melanin synthesis, has been implicated in the dedifferentiation of malignant… Expand
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Highly Cited
1996
Highly Cited
1996
Tyrosinase was the first melanoma-associated antigen shown to be recognized by CD4+ T cells. In this study, we have identified… Expand
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Highly Cited
1994
Highly Cited
1994
A number of cytolytic T lymphocyte (CTL) clones derived from several melanoma patients have been found to recognize a majority of… Expand