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T-Cell Activation

Known as: T cell activation, T lymphocyte activation, T-lymphocyte activation 
T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in… 
National Institutes of Health

Related topics

Related topics

50 relations
Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood LymphocytesAnti-MART-1 TCR Retroviral Vector-Transduced Autologous TILAutologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T CellsAutologous Prostate Stem Cell Antigen-specific CAR T Cells BPX-601

Papers overview

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Highly Cited
2014
Highly Cited
2014
Immune regulation by intralymphatic immunotherapy with modular allergen translocation MAT vaccine
Allergen‐specific immunotherapy (SIT) faces problems related to side effects and limited efficacy. Direct administration of… 
Highly Cited
2000
Highly Cited
2000
Human Immunodeficiency Virus-Specific Circulating CD8 T Lymphocytes Have Down-Modulated CD3ζ and CD28, Key Signaling Molecules for T-Cell Activation
ABSTRACT Although human immunodeficiency virus (HIV)-infected subjects without AIDS have a high frequency of HIV-specific CD8 T… 
Highly Cited
1997
Highly Cited
1997
Artificial cell surface constructs for studying receptor-ligand contributions to lymphocyte activation.
Highly Cited
1996
Highly Cited
1996
Prolonged islet allograft acceptance in the absence of interleukin 4 expression.
Highly Cited
1996
Highly Cited
1996
Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice.
Previous studies from this laboratory have demonstrated that the chemokines RANTES (recombinant human regulated upon activation… 
Review
1994
Review
1994
An 'alternative' pathway of T cell activation.
T cell receptor mediated signals in T cell activation determine the specificity, while costimulatory/accessory signals are… 
Highly Cited
1992
Highly Cited
1992
Both T cell receptor (TcR)‐CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR‐CD3‐independent and CD45‐dependent activation of p56lck
T cell activation by triggering the T cell receptor (TcR)‐CD3 complex leads to a dramatic increase in tyrosine phosphorylation of… 
Highly Cited
1990
Highly Cited
1990
FcR-mediated crosslinking of Ta1 (CDw26) induces human T lymphocyte activation.
Highly Cited
1989
Highly Cited
1989
Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies.
CD4 can physically associate with the CD3-T-cell receptor complex as visualized in cocapping experiments. This association occurs… 
Highly Cited
1985
Highly Cited
1985
A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.
Antigen or concanavalin A activation of a murine T-cell hybrid specific for pigeon cytochrome c and restricted to the Ek alpha:Ek… 
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