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T-Cell Activation

Known as: T cell activation, T lymphocyte activation, T-lymphocyte activation 
T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
The adaptive immune system is equipped to eliminate both tumors and pathogenic microorganisms. It requires a series of complex… 
Highly Cited
2004
Highly Cited
2004
The adaptive immune response is initiated in secondary lymphoid organs by contact between antigen-bearing dendritic cells (DCs… 
Highly Cited
2002
Highly Cited
2002
The balance between pro and antiinflammatory cytokines secreted by T cells regulates both the initiation and perpetuation of… 
Highly Cited
2001
Highly Cited
2001
T-lymphocyte activation and immune function are regulated by co-stimulatory molecules. CD28, a receptor for B7 gene products, has… 
Highly Cited
2001
Highly Cited
2001
CD4+CD25+ regulatory T cells inhibit organ-specific autoimmune diseases induced by CD4+CD25− T cells and are potent suppressors… 
Highly Cited
2000
Highly Cited
2000
1α,25-Dihydroxyvitamin D3 (1,25(OH)2D3), the active form of vitamin D3, is a potent immunomodulatory agent. Here we show that… 
Highly Cited
2000
Highly Cited
2000
Whereas co-stimulation of the T-cell antigen receptor (TCR) and CD28 triggers T-cell activation, stimulation of the TCR alone may… 
Highly Cited
1998
Highly Cited
1998
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… 
Highly Cited
1997
Highly Cited
1997
The developmental commitment to a T helper 1 (Th1)- or Th2-type response can significantly influence host immunity to pathogens… 
Highly Cited
1995
Highly Cited
1995
RECEPTOR crosslinking of T-cell hybridomas induces cell activation followed by apoptosis1–6. This activation-induced cell death…