Skip to search formSkip to main contentSkip to account menu

T-Cell Activation

Known as: T cell activation, T lymphocyte activation, T-lymphocyte activation 
T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in… 
National Institutes of Health

Related topics

Related topics

50 relations
Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood LymphocytesAnti-MART-1 TCR Retroviral Vector-Transduced Autologous TILAutologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T CellsAutologous Prostate Stem Cell Antigen-specific CAR T Cells BPX-601

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Role of GITR in activation response of T lymphocytes.
In this study, we describe the generation and characterization of mice in which GITR gene (TNFRSF18 [tumor necrosis factor… 
Highly Cited
2000
Highly Cited
2000
Human Immunodeficiency Virus-Specific Circulating CD8 T Lymphocytes Have Down-Modulated CD3ζ and CD28, Key Signaling Molecules for T-Cell Activation
ABSTRACT Although human immunodeficiency virus (HIV)-infected subjects without AIDS have a high frequency of HIV-specific CD8 T… 
Highly Cited
1996
Highly Cited
1996
Prolonged islet allograft acceptance in the absence of interleukin 4 expression.
Review
1995
Review
1995
Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule- 4 receptors during T cell activation?
C Ytotoxic T lymphocyte-assodated molecule-4 (CTLA-4) is a lymphocyte cell surface receptor originally discovered in a search for… 
Review
1994
Review
1994
An 'alternative' pathway of T cell activation.
T cell receptor mediated signals in T cell activation determine the specificity, while costimulatory/accessory signals are… 
Highly Cited
1992
Highly Cited
1992
Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells
T-lymphocyte activation via the antigen receptor complex (TCR) results in accumulation of p21ras in the active GTP-bound state… 
Highly Cited
1992
Highly Cited
1992
Murine B7 antigen provides an efficient costimulatory signal for activation of murine T lymphocytes via the T-cell receptor/CD3 complex.
We demonstrate that the murine B7 (mB7) protein is a potent costimulatory molecule for the activation of resting murine CD4+ T… 
Highly Cited
1992
Highly Cited
1992
Both T cell receptor (TcR)‐CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR‐CD3‐independent and CD45‐dependent activation of p56lck
T cell activation by triggering the T cell receptor (TcR)‐CD3 complex leads to a dramatic increase in tyrosine phosphorylation of… 
Highly Cited
1989
Highly Cited
1989
Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies.
CD4 can physically associate with the CD3-T-cell receptor complex as visualized in cocapping experiments. This association occurs… 
Highly Cited
1985
Highly Cited
1985
A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.
Antigen or concanavalin A activation of a murine T-cell hybrid specific for pigeon cytochrome c and restricted to the Ek alpha:Ek… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)