T-Cell Activation

Known as: T cell activation, T lymphocyte activation, T-lymphocyte activation 
T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in… (More)
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
The adaptive immune response is initiated in secondary lymphoid organs by contact between antigen-bearing dendritic cells (DCs… (More)
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Highly Cited
2004
Highly Cited
2004
Toll-like receptors (TLRs) detect microbial infection and play an essential role in the induction of innate and adaptive immune… (More)
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Highly Cited
2002
Highly Cited
2002
DR3 is a death domain-containing receptor that is upregulated during T cell activation and whose overexpression induces apoptosis… (More)
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Highly Cited
2001
Highly Cited
2001
CD4(+)CD25(+) regulatory T cells inhibit organ-specific autoimmune diseases induced by CD4(+)CD25(-) T cells and are potent… (More)
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Highly Cited
1998
Highly Cited
1998
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… (More)
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Highly Cited
1998
Highly Cited
1998
During T cell activation, the engagement of costimulatory molecules is often crucial to the development of an effective immune… (More)
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Highly Cited
1997
Highly Cited
1997
The developmental commitment to a T helper 1 (Th1)- or Th2-type response can significantly influence host immunity to pathogens… (More)
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Highly Cited
1995
Highly Cited
1995
RECEPTOR crosslinking of T-cell hybridomas induces cell activation followed by apoptosis1–6. This activation-induced cell death… (More)
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Highly Cited
1995
Highly Cited
1995
OPTIMAL T-cell activation and T-cell expansion require triggering by T-cell antigen receptors and co-stimulatory signals provided… (More)
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Review
1994
Review
1994
T cell receptor mediated signals in T cell activation determine the specificity, while costimulatory/accessory signals are… (More)
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