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T-Cell Activation

Known as: T cell activation, T lymphocyte activation, T-lymphocyte activation 
T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Chimeric antigen receptor (CAR) T-cell therapy entails the genetic engineering of a patient’s T-cells to express membrane… Expand
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Highly Cited
2004
Highly Cited
2004
The adaptive immune response is initiated in secondary lymphoid organs by contact between antigen-bearing dendritic cells (DCs… Expand
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Highly Cited
2001
Highly Cited
2001
CD4+CD25+ regulatory T cells inhibit organ-specific autoimmune diseases induced by CD4+CD25− T cells and are potent suppressors… Expand
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Highly Cited
2001
Highly Cited
2001
T-lymphocyte activation and immune function are regulated by co-stimulatory molecules. CD28, a receptor for B7 gene products, has… Expand
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Highly Cited
2000
Highly Cited
2000
Whereas co-stimulation of the T-cell antigen receptor (TCR) and CD28 triggers T-cell activation, stimulation of the TCR alone may… Expand
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Highly Cited
1998
Highly Cited
1998
Peripheral tolerance may be maintained by a population of regulatory/suppressor T cells that prevent the activation of… Expand
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Highly Cited
1997
Highly Cited
1997
The developmental commitment to a T helper 1 (Th1)- or Th2-type response can significantly influence host immunity to pathogens… Expand
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Highly Cited
1995
Highly Cited
1995
RECEPTOR crosslinking of T-cell hybridomas induces cell activation followed by apoptosis1–6. This activation-induced cell death… Expand
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Highly Cited
1995
Highly Cited
1995
OPTIMAL T-cell activation and T-cell expansion require triggering by T-cell antigen receptors and co-stimulatory signals provided… Expand
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Highly Cited
1992
Highly Cited
1992
Activation of lymphocyte subpopulations was determined in conjunction with levels of cytokines in peripheral blood and… Expand
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