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Autologous Prostate Stem Cell Antigen-specific CAR T Cells BPX-601

Known as: Autologous PSCA-specific CAR T Cells BPX-601, BPX-601, Autologous PSCA-Specific Chimeric Antigen Receptor Engineered T Cells BPX-601 
A preparation of autologous T-lymphocytes expressing a chimeric antigen receptor (CAR) consisting of an anti-human prostate stem cell antigen (PSCA… 
National Institutes of Health

Related topics

Related topics

4 relations
Antigen SensitizationCytotoxic T-LymphocytesT-Cell Activationimmunopotentiation

Papers overview

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2018
2018
In utero and lactational exposure of DEHP increases the susceptibility of prostate carcinogenesis in male offspring through PSCA hypomethylation.
As an ubiquitous environmental endocrine disruptor, di(2-ethylhexyl) phthalate (DEHP) has been shown to interfere with the… 
2015
2015
Associations of Genetic Variants in the PSCA, MUC1 and PLCE1 Genes with Stomach Cancer Susceptibility in a Chinese Population
Background Several genetic variants including PSCA rs2294008 C>T and rs2976392 G>A, MUC1 rs4072037 T>C, and PLCE1 rs2274223 A>G… 
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2015
2015
PSCA rs2294008 C > T polymorphism contributes to gastric and bladder cancer risk
Background Previous studies suggested genetic variations in PSCA (prostate stem cell antigen) may confer the susceptibility of… 
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Review
2014
Review
2014
Association of a common genetic variant in prostate stem cell antigen with cancer risk
Introduction Polymorphisms in the prostate stem cell antigen (PSCA) gene have been hypothesized to increase the genetic… 
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2013
2013
Human prostate stem cell antigen and HSP70 fusion protein vaccine inhibits prostate stem cell antigen-expressing tumor growth in mice.
Prostate stem cell antigen (PSCA) has been considered a potentially worthwhile target for prostate cancer therapy with its… 
Highly Cited
2012
Highly Cited
2012
Laryngeal preservation with induction chemotherapy for hypopharyngeal squamous cell carcinoma: 10-year results of EORTC trial 24891.
BACKGROUND We report the 10-year results of the EORTC trial 24891 comparing a larynx-preservation approach to immediate surgery… 
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2012
2012
Genetic variations of prostate stem cell antigen (PSCA) contribute to the risk of gastric cancer for Eastern Asians: a meta-analysis based on 16792 individuals.
The associations between polymorphisms of prostate stem cell antigen (PSCA-rs2294008C>T and -rs2976392G>A) and gastric cancer (GC… 
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2012
2012
A phase I/IIA study of AGS-PSCA for castration-resistant prostate cancer.
BACKGROUND This first-in-human phase I/IIA study was designed to evaluate the safety and pharmacokinetics (PKs) of AGS-PSCA a… 
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2012
2012
Association of the PSCA rs2294008 C>T polymorphism with gastric cancer risk: evidence from a meta-analysis.
BACKGROUND Multiple studies have reported associations between the PSCA rs2294008 C>T polymorphism and GC, but susceptibility has… 
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2005
2005
Therapeutic potential of AGS-PSCA: A fully human monoclonal antibody to prostate stem cell antigen (PSCA) for the treatment of prostate and pancreatic cancers
4722 Background: PSCA is a 123 amino acid GPI-linked surface antigen that is expressed in approximately 80% of prostate cancers… 
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