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Autologous Prostate Stem Cell Antigen-specific CAR T Cells BPX-601

Known as: Autologous PSCA-specific CAR T Cells BPX-601, BPX-601, Autologous PSCA-Specific Chimeric Antigen Receptor Engineered T Cells BPX-601 
A preparation of autologous T-lymphocytes expressing a chimeric antigen receptor (CAR) consisting of an anti-human prostate stem cell antigen (PSCA… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Antigen SensitizationCytotoxic T-LymphocytesT-Cell Activationimmunopotentiation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
In utero and lactational exposure of DEHP increases the susceptibility of prostate carcinogenesis in male offspring through PSCA hypomethylation.
As an ubiquitous environmental endocrine disruptor, di(2-ethylhexyl) phthalate (DEHP) has been shown to interfere with the… Expand
2015
2015
Associations of Genetic Variants in the PSCA, MUC1 and PLCE1 Genes with Stomach Cancer Susceptibility in a Chinese Population
Background Several genetic variants including PSCA rs2294008 C>T and rs2976392 G>A, MUC1 rs4072037 T>C, and PLCE1 rs2274223 A>G… Expand
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2015
2015
PSCA rs2294008 C > T polymorphism contributes to gastric and bladder cancer risk
Background Previous studies suggested genetic variations in PSCA (prostate stem cell antigen) may confer the susceptibility of… Expand
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Review
2014
Review
2014
Association of a common genetic variant in prostate stem cell antigen with cancer risk
Introduction Polymorphisms in the prostate stem cell antigen (PSCA) gene have been hypothesized to increase the genetic… Expand
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2013
2013
Human prostate stem cell antigen and HSP70 fusion protein vaccine inhibits prostate stem cell antigen-expressing tumor growth in mice.
Prostate stem cell antigen (PSCA) has been considered a potentially worthwhile target for prostate cancer therapy with its… Expand
Highly Cited
2012
Highly Cited
2012
Laryngeal preservation with induction chemotherapy for hypopharyngeal squamous cell carcinoma: 10-year results of EORTC trial 24891.
BACKGROUND We report the 10-year results of the EORTC trial 24891 comparing a larynx-preservation approach to immediate surgery… Expand
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2012
2012
A phase I/IIA study of AGS-PSCA for castration-resistant prostate cancer.
BACKGROUND This first-in-human phase I/IIA study was designed to evaluate the safety and pharmacokinetics (PKs) of AGS-PSCA a… Expand
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2012
2012
Genetic variations of prostate stem cell antigen (PSCA) contribute to the risk of gastric cancer for Eastern Asians: a meta-analysis based on 16792 individuals.
The associations between polymorphisms of prostate stem cell antigen (PSCA-rs2294008C>T and -rs2976392G>A) and gastric cancer (GC… Expand
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2012
2012
Association of the PSCA rs2294008 C>T polymorphism with gastric cancer risk: evidence from a meta-analysis.
BACKGROUND Multiple studies have reported associations between the PSCA rs2294008 C>T polymorphism and GC, but susceptibility has… Expand
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2005
2005
Therapeutic potential of AGS-PSCA: A fully human monoclonal antibody to prostate stem cell antigen (PSCA) for the treatment of prostate and pancreatic cancers
4722 Background: PSCA is a 123 amino acid GPI-linked surface antigen that is expressed in approximately 80% of prostate cancers… Expand
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