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tumor suppressor protein p73

Known as: p73, Protein, Tumor Protein p73 [Chemical/Ingredient], Protein p73, Tumor 
A homolog of p53 TUMOR SUPPRESSOR PROTEIN that encodes full-length trans-activating and N-terminally-truncated (DeltaN) isoforms. Detection of splice… 
National Institutes of Health

Papers overview

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2010
2010
The identification of agents that preferentially kill cancer cells while protecting normal cells offers the potential to overcome… 
Review
2008
Review
2008
Strategies to induce p53 for cancer therapy offer appeal but many tumors harbor inactivating p53 mutations. One way to address… 
Highly Cited
2006
Highly Cited
2006
p63 is essential for normal epithelial development and is overexpressed in the vast majority of squamous cell carcinomas (SCC… 
Highly Cited
2005
Highly Cited
2005
The metallic compound cisplatin has been used for many years to treat various human cancers. Here, we describe the cytostatic and… 
2005
2005
PURPOSE To study the relationship between protein expression and DNA methylation of a triad of cell-cycle regulatory genes known… 
2005
2005
p73, a member of the p53 family, is expressed from two separate promoters, generating TA and DeltaN variants. Each variant… 
2002
2002
Abstractp73 protein, a member of the p53 family protein, induce p21 and MDM2 transcription. In some carcinomas, the expression of… 
Highly Cited
1999
Highly Cited
1999
ABSTRACT Multiple adenovirus (Ad) early proteins have been shown to inhibit transcription activation by p53 and thereby to alter… 
Highly Cited
1999
Highly Cited
1999
p53 is mutated in ∼50% of human cancers, whereas mutations of the related p73 gene are rare. p73 can activate p53-responsive… 
1999
1999
The role of the recently identified first p53-homologue, p73, in neoplastic transformation is unknown. To elucidate p73 gene…