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tumor suppressor protein p73

Known as: p73, Protein, Tumor Protein p73 [Chemical/Ingredient], Protein p73, Tumor 
A homolog of p53 TUMOR SUPPRESSOR PROTEIN that encodes full-length trans-activating and N-terminally-truncated (DeltaN) isoforms. Detection of splice… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
p73, a member of the p53 family of transcription factors, is upregulated in response to DNA damage, inducing cell cycle arrest… Expand
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Highly Cited
2002
Highly Cited
2002
The p73 gene is a p53 homologue which induces apoptosis and inhibits cell proliferation. Although p73 maps at 1p36.3 and is… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT The growth inhibitory functions of p53 are controlled in unstressed cells by rapid degradation of the p53 protein. One… Expand
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Highly Cited
2000
Highly Cited
2000
The p73 protein, a homologue of the tumour-suppressor protein p53, can activate p53-responsive promoters and induce apoptosis in… Expand
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Review
2000
Review
2000
Abstract.cis-diamminedichloroplatinum(II) or cisplatin is a DNA-damaging agent that is widely used in cancer chemotherapy… Expand
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Highly Cited
2000
Highly Cited
2000
Strong stimulation of the T-cell receptor (TCR) on cycling peripheral T cells causes their apoptosis by a process called TCR… Expand
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Highly Cited
2000
Highly Cited
2000
Most human cancers harbour aberrations of cell-cycle control, which result in deregulated activity of the E2F transcription… Expand
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Highly Cited
1999
Highly Cited
1999
The protein p73 is a structural and functional homologue of the p53 tumour-suppressor protein but, unlike p53, it is not induced… Expand
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Highly Cited
1999
Highly Cited
1999
Cancer chemotherapeutic agents such as cisplatin exert their cytotoxic effect by inducing DNA damage and activating programmed… Expand
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Highly Cited
1999
Highly Cited
1999
The p73 gene is located on 1p36.2-3, a region that is frequently deleted in human cancer. Because p73 encodes for a protein that… Expand
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