p73 protein, human

Known as: p53-Like Transcription Factor, P73, p53-Related Protein 
Tumor protein p73 (636 aa, ~70 kDa) is encoded by the human TP73 gene. This protein is involved in the regulation of transcription, DNA damage… (More)
National Institutes of Health

Papers overview

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Review
2004
Review
2004
The tumor suppressor p53 is critically important in the cellular damage response and is the founding member of a family of… (More)
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Highly Cited
2003
Highly Cited
2003
We have used an affinity purification method to identify substrates of protein kinase B/Akt. One protein that associates with 14… (More)
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Highly Cited
2003
Highly Cited
2003
Most chemotherapeutic agents induce DNA damage, leading to p53 accumulation and apoptosis. The factors that determine… (More)
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Highly Cited
2002
Highly Cited
2002
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage… (More)
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Review
2002
Review
2002
As p53 and its homologue p73 have significant sequence and functional similarities, p73 might also be expected to act as a tumour… (More)
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Highly Cited
2000
Highly Cited
2000
p73 (ref. 1) has high homology with the tumour suppressor p53 (refs 2,3,4), as well as with p63, a gene implicated in the… (More)
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Highly Cited
1999
Highly Cited
1999
Cancer chemotherapeutic agents such as cisplatin exert their cytotoxic effect by inducing DNA damage and activating programmed… (More)
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Highly Cited
1999
Highly Cited
1999
The newly identified p53 homolog p73 can mimic the transcriptional activation function of p53. We investigated whether p73, like… (More)
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Highly Cited
1997
Highly Cited
1997
The protein p53 is the most frequently mutated tumour suppressor to be identified so far in human cancers. The ability of p53 to… (More)
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Highly Cited
1997
Highly Cited
1997
The protein p53 is the most frequently mutated tumour suppressor to be identified so far in human cancers,. The ability of p53 to… (More)
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