tumor necrosis factor receptor 1A

Known as: Receptors, Tumor Necrosis Factor, Type I [Chemical/Ingredient], CD120a Antigen, TNFR-I 
A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed… (More)
National Institutes of Health

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19 relations

Broader (2)

CD AntigensTumor Necrosis Factor Receptor
In BloodProcess of secretionReceptors, Tumor Necrosis Factor, Type IITNFRSF1A gene
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Narrower (4)

PEGylated soluble tumor necrosis factor receptor IPEGylated tumor necrosis factor alpha receptor 1TNFRSF1A protein, humanrecombinant human tumor necrosis factor-binding protein-1

Papers overview

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2007
2007
Expression of tumor necrosis factor receptor-1 in arterial wall cells promotes atherosclerosis.
OBJECTIVE Mechanisms by which tumor necrosis factor-alpha (TNF) contributes to atherosclerosis remain largely obscure. We… (More)
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Highly Cited
2007
Highly Cited
2007
The cytokine TNFα increases the proportion of DRG neurones expressing the TRPV1 receptor via the TNFR1 receptor and ERK activation
TNFalpha is involved in the generation of hyperalgesia in pathological states such as neuropathy and inflammation. The… (More)
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Highly Cited
2006
Highly Cited
2006
Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function.
OBJECTIVE To investigate the effect of mutations in the tumor necrosis factor receptor superfamily 1A (TNFRSF1A) gene on the… (More)
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2005
2005
Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant.
OBJECTIVE Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autoinflammatory syndrome associated with… (More)
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Highly Cited
2004
Highly Cited
2004
NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.
NF-kappaB inhibition promotes epidermal tumorigenesis; however, whether this reflects an underlying role in homeostasis or a… (More)
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Review
2001
Review
2001
Tumor necrosis factor receptor-associated factors (TRAFs)
Tumor necrosis factor receptor-associated factors (TRAFS) were initially discovered as adaptor proteins that couple the tumor… (More)
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Highly Cited
2001
Highly Cited
2001
Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways.
Tumor necrosis factor-alpha (TNF) and the ligand for receptor activator of NF-kappaB (RANKL) are abundant in sites of… (More)
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Highly Cited
1998
Highly Cited
1998
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor.
Tumor necrosis factor (TNF) can induce a variety of cellular responses at low picomolar concentrations. This is in apparent… (More)
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Highly Cited
1998
Highly Cited
1998
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis.
FADD (also known as Mort-1) is a signal transducer downstream of cell death receptor CD95 (also called Fas). CD95, tumor necrosis… (More)
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Highly Cited
1997
Highly Cited
1997
Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.
TNFR p60 (TNFR60) is the main mediator of TNF-induced apoptosis, although in some cells TNFR80 is also involved. TNFR80-dependent… (More)
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