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TNFRSF1A gene

Known as: TNFR60, TUMOR NECROSIS FACTOR-ALPHA RECEPTOR, TUMOR NECROSIS FACTOR RECEPTOR 1 
This gene modulates a variety of cellular functions such as apoptosis and inflammatory responses.
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisCell Death Signaling ProcessCell SurvivalCytokine Signaling Process

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TNFRSF1A wt Allele

Papers overview

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Review
2009
Review
2009
The Multiple Roles of the Innate Immune System in the Regulation of Apoptosis and Inflammation in the Brain
Central nervous system (CNS) tissues contain cells (i.e. glia and neurons) that have innate immune functions. These cells express… 
Highly Cited
2008
Highly Cited
2008
Adherence to healthy eating patterns is associated with higher circulating total and high-molecular-weight adiponectin and lower resistin concentrations in women from the Nurses' Health Study.
BACKGROUND Adherence to a healthy dietary pattern, such as the Alternate Healthy Eating Index (AHEI), is associated with a lower… 
Highly Cited
2006
Highly Cited
2006
Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS).
Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is an autosomal dominant systemic autoinflammatory… 
Highly Cited
2006
Highly Cited
2006
Recombinant Human TNFRSF1A (r-hTBP1) Inhibits the Development of Endometriosis in Baboons: A Prospective, Randomized, Placebo- and Drug-Controlled Study1
Abstract Endometriosis is associated with chronic inflammation, including an increased macrophage activity with increased… 
Highly Cited
2003
Highly Cited
2003
Fasting plasma leptin, tumor necrosis factor-alpha receptor 2, and monocyte chemoattracting protein 1 concentration in a population of glucose-tolerant and glucose-intolerant women: impact on…
OBJECTIVE Leptin and tumor necrosis factor (TNF)-alpha are associated with insulin resistance and cardiovascular disease. In… 
Review
2000
Review
2000
TNFRSF1A mutations and autoinflammatory syndromes.
Highly Cited
2000
Highly Cited
2000
Activation of nuclear factor κB in hepatitis C virus infection: Implications for pathogenesis and hepatocarcinogenesis
The hepatitis C virus (HCV) core protein is a multifunctional protein. It may bind to the death domain of tumor necrosis factor… 
Highly Cited
1998
Highly Cited
1998
TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60.
Costimulation of TNFR80 can strongly enhance TNFR60-induced cell death. In this study, we show that this enhancement is TNFR60… 
Highly Cited
1997
Highly Cited
1997
In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis
The significance of tumor necrosis factor receptor 1 (TNFR1) for TNF function in vivo is well documented, whereas the role of… 
Highly Cited
1996
Highly Cited
1996
Direct activation of porcine endothelial cells by human natural killer cells.
Endothelial cell (EC) activation is a consistent feature of discordant xenograft rejection. Treatment of xenograft recipients… 
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