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TNFRSF1A gene

Known as: TNFR60, TUMOR NECROSIS FACTOR-ALPHA RECEPTOR, TUMOR NECROSIS FACTOR RECEPTOR 1 
This gene modulates a variety of cellular functions such as apoptosis and inflammatory responses.
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisCell Death Signaling ProcessCell SurvivalCytokine Signaling Process

Narrower (1)

TNFRSF1A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
TNF receptor-associated periodic syndrome (TRAPS): Description of a novel TNFRSF1A mutation and response to etanercept
TRAPS is the most common of the autosomal dominant periodic fever syndromes. It is caused by mutations in the TNFRSF1A gene… 
2008
2008
Treatment with dextromethorphan improves endothelial function, inflammation and oxidative stress in male heavy smokers
Summary.  Background: Dextromethorphan (DM) is reported to reduce the inflammation‐mediated degeneration of dopaminergic neurons… 
Highly Cited
2007
Highly Cited
2007
Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect
Tumor necrosis factor (TNF) initiates local inflammation by triggering endothelial cells (EC) to express adhesion molecules for… 
Highly Cited
2006
Highly Cited
2006
A tumor necrosis factor receptor 1-dependent conversation between central nervous system-specific T cells and the central nervous system is required for inflammatory infiltration of the spinal cord.
We examined the role of tumor necrosis factor receptor 1 (TNFR1) in inflammation initiated by the adoptive transfer of central… 
Highly Cited
2001
Highly Cited
2001
Death Domain Mutagenesis of KILLER/DR5 Reveals Residues Critical for Apoptotic Signaling*
The Fas/tumor necrosis factor (TNF)/TRAIL receptors signal death through a cytoplasmic death domain (DD) containing six α-helices… 
1998
1998
Cooperative Signaling by Tumor Necrosis Factor Receptors CD120a (p55) and CD120b (p75) in the Expression of Nitric Oxide and Inducible Nitric Oxide Synthase by Mouse Macrophages*
Tumor necrosis factor-α (TNFα) is recognized by the cell-surface receptors CD120a (p55) and CD120b (p75). In the present study… 
Highly Cited
1996
Highly Cited
1996
Apoptosis in adult mouse testis induced by experimental cryptorchidism.
Induction of cryptorchidism in the mouse causes infertility due to disruption of spermatogenesis including reduction of germ… 
1996
1996
A role for tumor necrosis factor-alpha in the increased mortality associated with Vibrio vulnificus infection in the presence of hepatic dysfunction.
OBJECTIVE The present study was designed to evaluate whether pre-existing hepatic dysfunction (cirrhosis) leads to increased… 
1995
1995
Activation of p42mapk/erk2 following engagement of tumor necrosis factor receptor CD120a (p55) in mouse macrophages.
Cross-linking of the dichotomous cell surface receptors for TNF-alpha (CD120a (p55) and CD120b (p75)) induces the activation of a… 
Highly Cited
1994
Highly Cited
1994
TNF receptor signal transduction. Ligand-dependent stimulation of a serine protein kinase activity associated with (CD120a) TNFR60.
TNF is a pluripotent cytokine that mediates activities through two distinct receptors of 55 to 60 kDa (CD120a, known as TNFR60… 
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