Skip to search formSkip to main contentSkip to account menu

tryptophan catabolic process

Known as: tryptophan breakdown, tryptophan catabolism, tryptophan degradation 
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. [ISBN… 
National Institutes of Health

Related topics

Related topics

1 relation

Narrower (1)

tryptophanase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
ObjectivesIndoleamine-2,3-Dioxygenase (IDO) is an immunosuppressive molecule inducible in various cells. In addition to classic… 
Highly Cited
2007
Highly Cited
2007
Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells.
Indoleamine 2,3-dioxygenase (IDO) is a novel immunosuppressive agent expressed in some subsets of normal and neoplastic cells… 
Highly Cited
2007
Highly Cited
2007
Characterization of the Kynurenine Pathway in Human Neurons
The kynurenine pathway is a major route of l-tryptophan catabolism producing neuroactive metabolites implicated in… 
Highly Cited
2007
Highly Cited
2007
The Indoleamine 2,3-Dioxygenase Pathway Is Essential for Human Plasmacytoid Dendritic Cell-Induced Adaptive T Regulatory Cell Generation.
Plasmacytoid dendritic cells (PDCs) are a unique DC subset that plays a critical role in regulating innate and adaptive immune… 
Review
2004
Review
2004
IDO and tolerance to tumors.
Highly Cited
2004
Highly Cited
2004
Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease
Highly Cited
2000
Highly Cited
2000
Oxidation of indole by cytochrome P450 enzymes.
Indole is a product of tryptophan catabolism by gut bacteria and is absorbed into the body in substantial amounts. The compound… 
Highly Cited
1994
Highly Cited
1994
Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence
Previous studies have shown that the immune-regulated cytokine gamma interferon (IFN-gamma) activates host cells to restrict… 
Highly Cited
1989
Highly Cited
1989
Characteristics of interferon induced tryptophan metabolism in human cells in vitro.
Highly Cited
1986
Highly Cited
1986
Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase.
Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase was characterized, taking advantage of its induction by… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)