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tryptophan catabolic process
Known as:
tryptophan breakdown
, tryptophan catabolism
, tryptophan degradation
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. [ISBN…
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National Institutes of Health
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tryptophanase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease.
Hui-Ming Lin
,
Shelley Edmunds
,
N. Helsby
,
L. Ferguson
,
D. Rowan
Journal of Proteome Research
2009
Corpus ID: 25112000
Crohn's disease is an inflammatory disorder of the bowel, believed to arise from the dysregulation of intestinal mucosal immunity…
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Highly Cited
2008
Highly Cited
2008
Differential immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO) on primary human CD4+ and CD8+ T cells
Farshad Forouzandeh
,
R. Jalili
,
M. Germain
,
V. Duronio
,
A. Ghahary
Molecular and Cellular Biochemistry
2008
Corpus ID: 6130719
We have previously demonstrated that indoleamine 2,3-dioxygenase (IDO) expression by skin cells generates a tryptophan deficient…
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Review
2006
Review
2006
Toll‐like receptor 9‐mediated induction of the immunosuppressive pathway of tryptophan catabolism
F. Fallarino
,
P. Puccetti
European Journal of Immunology
2006
Corpus ID: 23700118
A series of recent studies, including an article in this issue of the European Journal of Immunology, have demonstrated that the…
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Highly Cited
2005
Highly Cited
2005
Tryptophan degradation in patients with gynecological cancer correlates with immune activation.
K. Schroecksnadel
,
C. Winkler
,
L. Fuith
,
D. Fuchs
Cancer Letters
2005
Corpus ID: 21372379
2005
2005
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12
C. Orabona
,
E. Tomasello
,
+8 authors
U. Grohmann
European Journal of Immunology
2005
Corpus ID: 429942
DAP12 is an immunoreceptor tyrosine‐based activation motif‐bearing membrane adapter molecule expressed by different cell types…
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Highly Cited
2003
Highly Cited
2003
Longitudinal study of tryptophan degradation during and after pregnancy.
K. Schröcksnadel
,
B. Widner
,
+4 authors
D. Fuchs
Life Science
2003
Corpus ID: 20604370
Highly Cited
2003
Highly Cited
2003
Atorvastatin suppresses interferon‐γ‐induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines
G. Neurauter
,
B. Wirleitner
,
Andreas Laich
,
H. Schennach
,
Günter Weiss
,
Dietmar Fuchs
Clinical and Experimental Immunology
2003
Corpus ID: 10529247
Inhibitors of 3‐hydroxy‐3methylglutaryl‐co‐enzyme A (HMG‐CoA) reductase, so‐called statins, are used in medical practice because…
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Highly Cited
2001
Highly Cited
2001
The role of l‐tryptophan transport in l‐tryptophan degradation by indoleamine 2,3‐dioxygenase in human placental explants
Y. Kudo
,
C. Boyd
Journal of Physiology
2001
Corpus ID: 24797572
1 The physiological importance of l‐tryptophan transport for placental indoleamine 2,3‐dioxygenase‐mediated degradation of l…
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Highly Cited
1999
Highly Cited
1999
Replication of Toxoplasma gondii, but NotTrypanosoma cruzi, Is Regulated in Human Fibroblasts Activated with Gamma Interferon: Requirement of a Functional JAK/STAT Pathway
I. P. Ceravolo
,
A. C. Chaves
,
C. A. Bonjardim
,
D. Sibley
,
A. Romanha
,
R. Gazzinelli
Infection and Immunity
1999
Corpus ID: 37060661
ABSTRACT To study the role of tryptophan degradation by indoleamine 2,3-dioxygenase (INDO) in the control of Trypanosoma cruzior…
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Highly Cited
1998
Highly Cited
1998
Inhibition of Chlamydia pneumoniae replication in HEp-2 cells by interferon-gamma: role of tryptophan catabolism.
Sheetal J. Mehta
,
Richard D. Miller
,
Julio A. Ramirez
,
J. Summersgill
Journal of Infectious Diseases
1998
Corpus ID: 26535906
Interferon-gamma (IFN-gamma) induces tryptophan catabolism in HEp-2 cells, possibly via stimulation of host cell indoleamine-2,3…
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