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trovirdine

Known as: 1-(5-Bromo-2-pyridyl)-3-(2-(2-pyridyl)ethyl)-2-thiourea 
A thiourea non-nucleoside reverse transcriptase inhibitor.
National Institutes of Health

Papers overview

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2002
2002
ABSTRACT A series of eleven heterodimers containing both a nucleoside analogue (d4U, d4T) and a non-nucleoside type inhibitor… Expand
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2000
2000
Chiral derivatives of two cyclohexylethyl halopyridyl thiourea compounds (HI-509 and HI-510), two alpha-methyl benzyl halopyridyl… Expand
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1999
1999
The novel thiourea compound N-[2-(2,5-dimethoxyphenylethyl)]-N'-[2-(5-bromopyridyl)]-thi ourea (HI-236) targeting the non… Expand
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Review
1999
Review
1999
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside reverse transcriptase inhibitors… Expand
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1999
1999
We have replaced the pyridyl ring of trovirdine with an alicyclic cyclohexenyl, adamantyl or cis-myrtanyl ring. Only the… Expand
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1999
1999
Sexually active women represent the fastest growing HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome… Expand
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1998
1998
A novel computer model of the HIV reverse transcriptase (RT) non-nucleoside inhibitor (NNI) binding pocket, which was generated… Expand
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1998
1998
A series of novel phenethylthiazolylthiourea (PETT) derivatives targeting the nonnucleoside inhibitor (NNI) binding site of HIV… Expand
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1996
1996
Phenylethylthiazolylthiourea (PETT) derivatives have been identified as a new series of non-nucleoside inhibitors of HIV-1 RT… Expand
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1995
1995
A new class of very potent and selective non-nucleoside inhibitors of HIV reverse transcriptase (RT) has recently been identified… Expand
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