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Seroprevalence and risk factors of Toxoplasma gondii in Tibetan Sheep in Gansu province, Northwestern China
TLDR
The results of this study indicate that Tibetan sheep in Gansu province are frequently exposed to T. gondii, posing a direct threat to the public health as well as to local sheep industry. Expand
Analysis of miRNA expression profiling in mouse spleen affected by acute Toxoplasma gondii infection.
TLDR
A changed miRNA regulation network in mouse spleen infected by T. gondii was showed, revealing the relationship among T. Gondii infection, gene regulation, apoptosis and cancer process alterations in infected spleen, and the validated targets of differently expressed miRNAs were significantly enriched in gene transcription regulation. Expand
Vaccination with a DNA vaccine encoding Toxoplasma gondii ROP54 induces protective immunity against toxoplasmosis in mice.
TLDR
The results demonstrate that the recombinant ROP54 plasmid can provide partial protection and might be a potential vaccine candidate against acute and chronic toxoplasmosis and demonstrated that pVAX-ROP54 induced significant cellular and humoral immune responses, which extended the survival time of immunized mice. Expand
Major parasitic diseases of poverty in mainland China: perspectives for better control
TLDR
The prevalence rates, geographical distributions, epidemic characteristics, risk factors, and clinical manifestations of parasitic diseases of poverty listed in the first issue of the journal Infectious Diseases of Poverty on 25 October 2012 are reviewed. Expand
The prevalence of antibodies to Toxoplasma gondii in horses in Changji Hui Autonomous Prefecture, Xinjiang, northwestern China.
TLDR
The results indicated that T. gondii is widely prevalent in horses in Xinjiang, northwestern China, representing a serious threat to animal and human health, and more careful measures should be performed to control and prevent T. Gondii infection in horses from Xinjiang. Expand
Immune responses and protection after DNA vaccination against Toxoplasma gondii calcium-dependent protein kinase 2 (TgCDPK2)
TLDR
It is demonstrated that pVAX-TgCDPK2 is a potential vaccine candidate against acute toxoplasmosis and could elicit special humoral and cellular responses, with higher levels of IgG antibody, and increased levels of Th1-type cytokines. Expand
Proteomic analysis of Fasciola hepatica excretory and secretory products (FhESPs) involved in interacting with host PBMCs and cytokines by shotgun LC-MS/MS
TLDR
The results showed that 14, 16, and 9 proteins in FhESPs could bind with IL2, IL17, and IFN-γ, respectively, which indicated that adult F. hepatica may evade the host immune responses through directly interplaying with cytokines. Expand
Seroprevalence and correlates of Toxoplasma gondii infection in dairy cattle in northwest China
TLDR
The results of this survey indicated the presence of T. gondii infection in dairy cattle in Gansu Province and NXHAR, which enriches the epidemiological data of Toxoplasma gond ii infection in China, and is helpful to strengthen prevention and control of the infection. Expand
Global Transcriptome Profiling of Multiple Porcine Organs Reveals Toxoplasma gondii-Induced Transcriptional Landscapes
TLDR
Findings not only show how Toxoplasma gondii infection alters porcine transcriptome in a tissue-specific manner, but also offer a gateway for testing new hypotheses regarding human response to T. gondII infection. Expand
Rapid and Visual Detection of Trichinella Spp. Using a Lateral Flow Strip-Based Recombinase Polymerase Amplification (LF-RPA) Assay
TLDR
The developed LF-RPA assay is presented as a new simple, specific, sensitive, rapid and convenient method for the detection of Trichinella infection in domestic animals. Expand
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