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tomopenem

A 1-beta-methylcarbapenem antibiotic with broad-spectrum activity against gram-positive and gram-negative bacteria. Tomopenem has a longer half-life… Expand
National Institutes of Health

Papers overview

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2011
2011
ABSTRACT Tomopenem (formerly CS-023) is a novel carbapenem with improved activity against diverse hospital pathogens, including… Expand
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2010
2010
ABSTRACT Tomopenem (formerly CS-023) is a novel carbapenem with broad-spectrum activities against diverse hospital pathogens… Expand
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2010
2010
The postantibiotic effect (PAE) of tomopenem was determined after a 2 h exposure of two strains of meticillin-susceptible and… Expand
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2009
2009
AIMS To investigate the effect of age and gender on the tolerability, safety and pharmacokinetics (PK) of tomopenem (RO4908463/CS… Expand
2008
2008
ABSTRACT Tomopenem (formerly CS-023) is a novel 1β-methylcarbapenem with broad-spectrum coverage of gram-positive and gram… Expand
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2008
2008
OBJECTIVES Tomopenem (CS-023) is a novel parenteral carbapenem with broad-spectrum activity against Gram-positive and -negative… Expand
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2008
2008
ABSTRACT Tomopenem (formerly CS-023), a novel 1β-methylcarbapenem, exhibited high affinity for penicillin-binding protein (PBP) 2… Expand
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2008
2008
ABSTRACT The antibacterial effects (ABE) of tomopenem (formerly RO4908463/CS-023) against seven Staphylococcus aureus strains… Expand
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2008
2008
ABSTRACT The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other… Expand
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2008
2008
ABSTRACT The objective of this study was to assess the impact of impaired renal function on the pharmacokinetics of tomopenem… Expand
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