thiopurine

Known as: thiopurines 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND & AIMS Patients with inflammatory bowel disease (IBD) who have been exposed to thiopurines might have an increased… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Reports of an increased risk of lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel… (More)
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Review
2008
Review
2008
Thiopurines have diverse clinical applications and their long-term use as anti-rejection drugs in transplant patients has been… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Firm recommendations about the way thiopurine drugs are introduced and the use of thiopurine methyltransferase (TPMT… (More)
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Highly Cited
2004
Highly Cited
2004
The thiopurine S-methyltransferase (TPMT) genetic polymorphism has a significant clinical impact on the toxicity of thiopurine… (More)
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Highly Cited
2002
Highly Cited
2002
Mercaptopurines have been used as anticancer agents for more than 40 years, and most acute lymphoblastic leukemias are treated… (More)
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Highly Cited
2001
Highly Cited
2001
Thiopurine drugs are used to treat patients with neoplasia and autoimmune disease as well as transplant recipients. These agents… (More)
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Review
1999
Review
1999
Methyl conjugation is an important pathway in the biotransformation of many exogenous and endogenous compounds. Pharmacogenetic… (More)
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Review
1997
Review
1997
Advances in the molecular and immunologic characterization of leukemic cells have greatly aided the diagnosis and risk assignment… (More)
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Highly Cited
1978
Highly Cited
1978
A radiochemical micromethod for the determination of thiopurine methyltransferase (TPMT) activity in human red blood cells (RBC… (More)
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