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purine analog

Known as: analogs purine, analogues purine 
National Institutes of Health

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8 relations

Narrower (7)

Purine analogs, antimetabolites antineoplasticadenine analogazapurineguanine analog

Broader (1)

nucleobase analog

Papers overview

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2013
2013
Inhibition of DNA Glycosylases via Small Molecule Purine Analogs
Following the formation of oxidatively-induced DNA damage, several DNA glycosylases are required to initiate repair of the base… 
Review
2011
Review
2011
Systematic review of purine analog treatment for chronic lymphocytic leukemia: lessons for future trials
A systematic review of purine analogs revealed heterogeneity between trials in treatment effects on response and progression free… 
Review
2011
Review
2011
Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence
The purine analogs pentostatin and cladribine are effective treatments for hairy cell leukemia (HCL). However, alternative… 
2011
2011
Comprehensive proteomic analysis of the effects of purine analogs on human Raji B-cell lymphoma.
Cladribine (CdA) and fludarabine (FdAMP) are purine analogs that induce apoptosis in chronic lymphocytic leukemia and non-Hodgkin… 
2008
2008
Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)
Multidrug resistance (MDR) is the main obstacle to a successful chemotherapy of lung cancer. We tested the potential of… 
2008
2008
Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.
The advancement of gene therapy has been slowed, in part, by inefficient transduction of targeted cells and poor long-term… 
Highly Cited
1997
Highly Cited
1997
CVT-313, a Specific and Potent Inhibitor of CDK2 That Prevents Neointimal Proliferation*
The activity of cyclin-dependent kinase 2 (CDK2) is essential for progression of cells from G1 to the S phase of the mammalian… 
Review
1996
Review
1996
Purine Analogs for the Treatment of Low-Grade Lymphoproliferative Disorders.
PRIMARY PURPOSE: Low-grade lymphoproliferative disorders follow an indolent clinical course but are incurable with current… 
Highly Cited
1994
Highly Cited
1994
Effect of AIT-082, a purine analog, on working memory in normal and aged mice
1983
1983
8-Azaguanine versus 6-thioguanine: influence on frequency and expression time of induced HGPRT- mutations in Chinese hamster V79 cells.
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