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Proposals for the classification of the myelodysplastic syndromes
TLDR
It is now proposed that over 30% of bone marrow blasts will suffice for the diagnosis of acute myeloid leukaemia (AML) in any of its forms (M1‐M6) and recognition of the new category, RAEB in transformation, may throw light on the pathogenesis of AML.
Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative Group
Summary. A uniform system of classification and nomenclature of the acute leukaemias, at present lacking, should permit more accurate recording of the distribution of cases entered into clinical
Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group.
Excerpt The first proposals for the morphologic classification of the acute leukemias by the French-American-British (FAB) group (1) were put forward in the hope that they might serve as a basis fo...
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working
TLDR
The International Workshop on Chronic Lymphocytic Leukemia (IWCLL) to provide updated recommendations for the management of CLL in clinical trials and general practice is provided.
iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL.
TLDR
Recommendations include a revised version of the iwCLL response criteria, an update on the use of MRD status for clinical evaluation, and recommendations regarding the assessment and prophylaxis of viral diseases during management of CLL.
The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL.
TLDR
A scoring system that gives for each of the most common marker profile in CLL a value of 1 or 0 according to whether it is typical or atypical for CLL will facilitate the diagnosis of B-lymphoproliferative disorders and improve their classification.
Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia.
TLDR
The clinical course was progressive with a median survival of 7.5 months and the response rate increased to 58% in patients with a CD4+ CD8- phenotype, and a subgroup of patients may benefit from deoxycoformycin.
Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML‐MO)
TLDR
A form of acute myeloid leukaemia (AML), designated AML‐MO, with minimalMyeloid differentiation, not included previously in the FAB classification is described and its clinical and biological significance is not yet apparent.
The chronic myeloid leukaemias: guidelines for distinguishing chronic granulocytic, atypical chronic myeloid, and chronic myelomonocytic leukaemia: Proposals by the French ‐ American ‐ British
TLDR
A statstical model is developed that confirms that CGL, aCML and CMML can be distinguished from each other with reasonable success employing five quantitative parameters and one qualitative parameter.
Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b).
TLDR
The replacement of CD22 by SN8 in the original scoring system significantly increases its potential to discriminate between CLL and other B-cell lymphoproliferative diseases.
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