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azapurine

 
National Institutes of Health

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3 relations

Broader (3)

Azo CompoundsPurine Nucleosidespurine analog

Papers overview

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2011
2011
High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase
Background Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent… Expand
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2010
2010
In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi.
Seven ternary nickel(II) complexes (three previously described and four firstly described here) with an azapurine derivative (the… Expand
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1996
1996
Fluorescence emission properties of 8-azapurines and their nucleosides, and application to the kinetics of the reverse synthetic reaction of purine nucleoside phosphorylase.
An extensive study has been made of the fluorescence emission properties of the neutral and ionic forms in aqueous medium of the… Expand
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1992
1992
Inhibition of adenosine deaminase by azapurine ribonucleosides.
We have synthesized several 8-azapurine nucleosides as inhibitors of adenosine deaminase. The presence of a nitrogen on the… Expand
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1984
1984
Synthesis and antiviral evaluation of carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines.
Carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8- azapurines were… Expand
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1975
1975
THE SYNTHESIS AND EVALUATION OF AZAPURINE NUCLEOSIDES AS CYTOTOXIC AGENTS *
Interest in the azapurines dates back to discovery of the antibacterial’ and antitumor activity’ of 8-azaguanine, which is toxic… Expand
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1972
1972
Azapurine nucleosides. 2. Synthesis and antiviral activity of 7-amino-3- -D-arabinofuranosyl-v-triazolo (4,5-d)pyrimidine and related nucleosides.
 
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Highly Cited
1972
Highly Cited
1972
Azapurine nucleosides. 1. Synthesis and antitumor activity of certain 3- -D-ribofuranosyl- and 2'-deoxy-D-ribofuranosyl-v-triazolo(4,5-d)pyrimidines.
 
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1965
1965
UTILIZATION OF 8-AZAPURINES BY YEASTS.
At concentrations normally inhibitory to certain bacteria, 8-azaadenine and 8-azaguanine are metabolised by the yeast strains… Expand
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Highly Cited
1957
Highly Cited
1957
Pyrazolopyrimidines as inhibitors and substrates of xanthine oxidase.
A variety of purine and azapurine analogues have been shown to serve as substrates for and inhibitors of xanthine oxidase. Thus… Expand
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