azapurine
National Institutes of Health
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Background Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent…
Seven ternary nickel(II) complexes (three previously described and four firstly described here) with an azapurine derivative (the…
We have synthesized several 8-azapurine nucleosides as inhibitors of adenosine deaminase. The presence of a nitrogen on the…
Carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8- azapurines were…
Interest in the azapurines dates back to discovery of the antibacterial’ and antitumor activity’ of 8-azaguanine, which is toxic…
8-Azapurine (1) and its 2-amino-, 2-thioxo-, and 2-oxo-derivatives reacted with ethyl cyanoacetate to form 4-aminomethyleneamino…