thioester

 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
PINK1 (PTEN induced putative kinase 1) and PARKIN (also known as PARK2) have been identified as the causal genes responsible for… (More)
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Highly Cited
2012
Highly Cited
2012
The linear ubiquitin chain assembly complex (LUBAC) is a RING E3 ligase that regulates immune and inflammatory signalling… (More)
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Review
2009
Review
2009
E3 ligases confer specificity to ubiquitination by recognizing target substrates and mediating transfer of ubiquitin from an E2… (More)
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Highly Cited
2007
Highly Cited
2007
Ubiquitin-like proteins (UBLs) are conjugated by dynamic E1–E2–E3 enzyme cascades. E1 enzymes activate UBLs by catalysing UBL… (More)
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Highly Cited
2005
Highly Cited
2005
The mammalian complement system is a phylogenetically ancient cascade system that has a major role in innate and adaptive… (More)
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Highly Cited
2001
Highly Cited
2001
We characterize a novel hemocyte-specific acute phase glycoprotein from the malaria vector, Anopheles gambiae. It shows… (More)
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Highly Cited
2000
Highly Cited
2000
[reaction: see text] The technique of native chemical ligation enables the total chemical synthesis of proteins. This method is… (More)
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Highly Cited
1998
Highly Cited
1998
A protein semisynthesis method-expressed protein ligation-is described that involves the chemoselective addition of a peptide to… (More)
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Highly Cited
1996
Highly Cited
1996
A KEY step in the elimination of pathogens from the body is the covalent binding of complement proteins C3 and C4 to their… (More)
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Highly Cited
1992
Highly Cited
1992
Proteolipid protein (PLP), the major integral membrane protein of central nervous system myelin, contains 14 cysteine residues… (More)
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