tezacitabine

Known as: 2'-Deoxy-2'-(fluoromethylene)cytidine, Cytidine, 2'-deoxy-2'-(fluoromethylene)-, (2E)-, (E)-2'-deoxy-2'-(fluoromethylene)cytidine 
A synthetic pyrimidine nucleoside analogue with potential antineoplastic activity. Phosphorylated by cellular kinases, tezacitabine is converted into… (More)
National Institutes of Health

Papers overview

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2012
2012
B3LYP/6-311+G(2d,p)//B3LYP/6-31+G(d) density functional theory calculations were employed to explore the kinetics and… (More)
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2007
2007
Endothelial dysfunction is associated with cardiovascular diseases and their risk factors (CVRF), and flow-mediated dilation (FMD… (More)
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2005
2005
BACKGROUND Tezacitabine [(E)-2'-deoxy-2'-(fluoromethylene) cytidine; FMdC] is a novel nucleoside analog with potent… (More)
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2003
2003
BACKGROUND The authors performed a dose escalation study of cisplatin and the novel deoxycytidine analog, tezacitabine, to… (More)
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Review
2000
Review
2000
Tezacitabine (MDL-101731, KW-2331, FMdC), an antimetabolite deoxycytidine analog, is an irreversible ribonucleotide reductase… (More)
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1999
1999
Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in cells by HPLC is an analytical challenge… (More)
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1999
1999
(E)-2'-deoxy-2'-(fluoromethylene) cytidine (FMdC), a novel inhibitor of ribonucleotide-diphosphate reductase, has been shown to… (More)
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1997
1997
The fmdA and fmdB genes encoding formamidase and a putative regulatory protein, respectively, from the methylotrophic bacterium… (More)
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1994
1994
(E)-2'-Deoxy-2'-(fluoromethylene)cytidine (MDL 101,731) is a mechanism-based inhibitor of ribonucleoside diphosphate reductase (J… (More)
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