tetrahydrodeoxycorticosterone

GABAA receptors are the major ionotropic inhibitory neurotransmitter receptors. The endocannabinoid system is a lipid signaling… Expand

Social isolation of rats immediately after weaning is associated to a reduction in the cerebrocortical and plasma concentrations… Expand

Allopregnanolone (ALLO) and tetrahydrodeoxycorticosterone (THDOC) are potent positive allosteric modulators of GABA action at… Expand

Stress affects seizure susceptibility in animals and humans, but the underlying mechanisms are obscure. Here, we provide evidence… Expand

The progesterone derivative 3 alpha-hydroxy-5 alpha-pregnan-20 one (allopregnanolone/AP) and the deoxycorticosterone derivative 3… Expand

Stressful experience during early brain development has been shown to produce profound alterations in several mechanisms of… Expand

1. The effects of progesterone, its A-ring-reduced metabolites, allopregnanolone, tetrahydroxydeoxycorticosterone and the… Expand

To investigate whether progesterone metabolites' antinociceptive effects correlate with their previously established binding… Expand

The potentiation of gamma-aminobutyric acid (GABA) receptor-mediated 36Cl- uptake by various steroids has been characterized in… Expand

Twenty five patients (10 males and 15 females) aged 0-23 yr with congenital adrenal hyperplasis due to 11 beta-hydroxylase… Expand