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allotetrahydrodeoxycorticosterone

National Institutes of Health

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tetrahydrodeoxycorticosterone

Papers overview

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Review
2013
Review
2013
Neurosteroid interactions with synaptic and extrasynaptic GABAA receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability
RationaleNeurosteroids are steroids synthesized within the brain with rapid effects on neuronal excitability. Allopregnanolone… Expand
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Review
2010
Review
2010
Neurosteroids: endogenous role in the human brain and therapeutic potentials.
  • D. Reddy
  • Progress in brain research
  • 2010
    • Corpus ID: 35380415
This chapter provides an overview of neurosteroids, especially their impact on the brain, sex differences and their therapeutic… Expand
Highly Cited
2005
Highly Cited
2005
GABAA Receptor-Mediated Tonic Inhibition in Thalamic Neurons
Tonic GABAA receptor-mediated inhibition is typically generated byδ subunit-containing extrasynaptic receptors. Because the… Expand
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Highly Cited
2004
Highly Cited
2004
Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice
Many of the biological actions of progesterone are mediated through the progesterone receptor (PR), a nuclear transcription… Expand
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Highly Cited
2002
Highly Cited
2002
Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABAA Receptor Function and Seizure Susceptibility
Stress affects seizure susceptibility in animals and humans, but the underlying mechanisms are obscure. Here, we provide evidence… Expand
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Highly Cited
2001
Highly Cited
2001
Enhanced Anticonvulsant Activity of Neuroactive Steroids in a Rat Model of Catamenial Epilepsy
Summary:  Purpose: Perimenstrual catamenial epilepsy may in part be due to withdrawal of the endogenous progesterone‐derived… Expand
Review
2001
Review
2001
Stress and neuroactive steroids.
The discovery that the endogenous steroid derivatives 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone, or 3 alpha,5… Expand
Highly Cited
2000
Highly Cited
2000
Social Isolation‐Induced Decreases in Both the Abundance of Neuroactive Steroids and GABAA Receptor Function in Rat Brain
The effects of social isolation on behavior, neuroactive steroid concentrations, and GABAA receptor function were investigated in… Expand
Highly Cited
1999
Highly Cited
1999
Ethanol markedly increases "GABAergic" neurosteroids in alcohol-preferring rats.
Alcohol administration (1 g/kg, i.p.) increased the levels of the neurosteroids 3alpha-hydroxy-5alpha-pregnan-20-one… Expand
Highly Cited
1998
Highly Cited
1998
Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.
The relation between changes in brain and plasma concentrations of neurosteroids and the function and structure of gamma… Expand
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