allotetrahydrodeoxycorticosterone

Neurosteroids are synthesized in the brain and modulate brain excitability. There is increasing evidence of their sedative… (More)

In the past decades considerable evidence has emerged that so-called neuroactive steroids do not only act as transcriptional… (More)

Several studies have shown the influence of the oestrous cycle on anxiety levels and the important role of progesterone in this… (More)

Tonic GABAA receptor-mediated inhibition is typically generated by delta subunit-containing extrasynaptic receptors. Because the… (More)

Stress affects seizure susceptibility in animals and humans, but the underlying mechanisms are obscure. Here, we provide evidence… (More)

Our previous study showed that the neurosteroids pregnenolone sulfate (PS) and epipregnanolone stimulated and blocked… (More)

The discovery that the endogenous steroid derivatives 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone, or 3 alpha,5… (More)

The effects of social isolation on behavior, neuroactive steroid concentrations, and GABA(A) receptor function were investigated… (More)

Alcohol administration (1 g/kg, i.p.) increased the levels of the neurosteroids 3alpha-hydroxy-5alpha-pregnan-20-one… (More)

The relation between changes in brain and plasma concentrations of neurosteroids and the function and structure of gamma… (More)