Skip to search formSkip to main contentSkip to account menu

terbinafine

Known as: terbinafine [Chemical/Ingredient], (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene Methanamine, Terbinafinum 
A synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking… 
National Institutes of Health

Related topics

Related topics

26 relations
AllylamineCandidiasis, Chronic MucocutaneousDrug AllergyErgosterol Synthesis Inhibitors [MoA]

Broader (3)

Antifungal AgentsEnzyme InhibitorsNaphthalenes

Narrower (3)

LamisilSilka Creamterbinafine 250 MG Oral Tablet

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Development of a Sigma‐2 Receptor affinity filter through a Monte Carlo based QSAR analysis
Highly Cited
2009
Highly Cited
2009
Trans-ungual iontophoretic delivery of terbinafine.
Successful treatment of deep-seated nail infections remains elusive as the delivery of efficacious levels of antifungal drug to… 
2008
2008
Heteroallyl-containing 5-nitrofuranes as new anti-Trypanosoma cruzi agents with a dual mechanism of action.
Highly Cited
2004
Highly Cited
2004
In vitro interactions of licensed and novel antifungal drugs against Fusarium spp.
Highly Cited
2001
Highly Cited
2001
Single-blind, randomized, prospective study of sequential itraconazole and terbinafine pulse compared with terbinafine pulse for the treatment of toenail onychomycosis.
OBJECTIVE Efficacy and safety of sequential pulse therapy with itraconazole and terbinafine were compared with pulse terbinafine… 
Review
1999
Review
1999
Parasitological cure of Chagas disease: is it possible? Is it relevant?
Nearly 90 million people (about a quarter ofthe Latin American population) live in zones whereChagas disease is endemic while 18… 
Highly Cited
1996
Highly Cited
1996
A 12–week treatment for dermatophyte toe onychomycosis terbinafine 250mg/day vs. itraconazole 200mg/day—a double‐blind comparative trial
Lamisil® (terbinafine) 250 mg daily and itraconazole 200 mg daily were compared in the treatment of dermalophyte toe… 
Highly Cited
1996
Highly Cited
1996
Postmarketing surveillance of oral terbinafine in the UK: report of a large cohort study.
1. The safety profile of terbinafine, the first orally active allylamine, was monitored in the UK in a post-marketing setting… 
Highly Cited
1995
Highly Cited
1995
Synthesis and structure-activity relationships of side-chain-substituted analogs of the allylamine antimycotic terbinafine lacking the central amino function.
Terbinafine is a therapeutically used inhibitor of fungal squalene epoxidase that has prompted extensive derivatization programs… 
Highly Cited
1990
Highly Cited
1990
Determination of terbinafine in nail samples during systemic treatment for onychomycoses
A combination of alkali treatment and proteinase K digestion was used to solubilize nail samples from patients with onychomycosis… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)