Skip to search formSkip to main contentSkip to account menu

temocillin

Known as: temocillin, (2S-(2alpha,5alpha,6alpha))-isomer 
A semisynthetic, narrow-spectrum, beta-lactamase-resistant penicillin with antibacterial activity. Temocillin binds to and inactivates penicillin… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Anti-Bacterial AgentsPenicillins

Narrower (1)

BRL 17421
Temocillin:Susc:Pt:Isolate:OrdQn:Gradient stripTemocillin:Susc:Pt:Isolate:OrdQn:MIC

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Clinical Evaluation of Temocillin in Urinary Tract Infections
SummaryA group of 27 female and 2 male urological patients, aged 19 to 80 years (mean 44 years), were treated with intravenous… 
2012
2012
Pharmacokinetics and Tissue Penetration of Temocillin
SummaryThe pharmacokinetics of intravenous (bolus) temocillin 1g were studied in 6 healthy male volunteers, and a cantharides… 
2012
2012
Biliary Concentrations of Temocillin
SummarySerum and bile concentrations of temocillin were measured after intravenous administration of 1g twice daily to 16… 
2012
2012
Temocillin Treatment of Serious Infections due to Gram-Negative Bacilli in an Intensive Care Unit
SummaryIn a group of 27 severely ill patients in an intensive care unit, 40 infections caused by Gram-negative bacilli were… 
1987
1987
Selection frequency of resistant variants by various beta-lactam antibiotics in clinical Enterobacter cloacae isolates.
The frequency of selection of resistant variants by 10 different broad-spectrum beta-lactam derivatives was evaluated for 10… 
1986
1986
BRL 20330, an oral prodrug of temocillin: bioavailability studies in man.
BRL 20330 is the o-methyl phenyl ester of temocillin which is well absorbed after oral administration and converted to temocillin… 
1986
1986
Antibacterial activity of resolved temocillin epimers.
The antibacterial activity of pure resolved R and S epimers of temocillin was determined in a variety of in-vitro test systems… 
1985
1985
Human pharmacokinetics of temocillin (BRL 17421) side chain epimers.
The pharmacokinetics of the side-chain epimers of temocillin were investigated in four healthy male subjects following a single… 
1984
1984
High-performance liquid chromatographic assay of temocillin and epimerisation of its diastereoisomers.
Assay of temocillin by a high-performance liquid chromatographic method that resolves the diastereoisomers is described and… 
1983
1983
Temocillin elimination in patients with varying degrees of renal failure.
Temocillin is a new penicillin combining activity against Gram-positive organisms, beta-lactamase stability and an exceptionally…