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Infrequent toxicities associated with certain drugs and drug classes have recently gained much attention from… Expand The quinolones have evolved from antibacterial agents with a limited spectrum of predominantly anti-gram-negative antimicrobial… Expand Four months after its approval in the United States, temafloxacin was withdrawn from the market worldwide because of frequent… Expand The MICs of four new quinolones, sparfloxacin (AT-4140, CI-978), PD 131628 (the active form of the prodrug CI-990), temafloxacin… Expand The in vitro activities of seven fluoroquinolones against 290 anaerobes were determined by agar dilution. CI-960 and WIN 57273… Expand Temafloxacin is a new antibacterial agent of the fluoroquinolone group. In comparison with ciprofloxacin, the current leading… Expand Tosufloxacin (A-61827) is the tosylate salt of A-60969 (T-3262). Temafloxacin (A-62254) is the hydrochloride salt of A-63004… Expand The activities of fluoroquinolones and a new macrolide against 30 clinical isolates of Mycobacterium tuberculosis were determined… Expand The in-vitro activity of temafloxacin compared with other quinolone antibiotics was evaluated using 579 bacterial strains and… Expand There is no effective therapy to treat Mycobacterium avium complex infection in patients with acquired immune deficiency syndrome… Expand