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tau-protein kinase activity

Known as: STK31, TTK, TPK 
Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. [EC:2.7.11.26, MetaCyc:TAU-PROTEIN-KINASE-RXN]
National Institutes of Health

Related topics

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3 relations
TTK Protein Kinasenegative regulation of tau-protein kinase activitypositive regulation of tau-protein kinase activity

Papers overview

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Highly Cited
2007
Highly Cited
2007
Use of a trapping agent for simultaneous capturing and high-throughput screening of both "soft" and "hard" reactive metabolites.
Glutathione (GSH) has been widely used for in vitro trapping and subsequently detecting reactive metabolites using liquid… 
Highly Cited
2003
Highly Cited
2003
Lithium Stabilizes the CCAAT/Enhancer-binding Protein α (C/EBPα) through a Glycogen Synthase Kinase 3 (GSK3)-independent Pathway Involving Direct Inhibition of Proteasomal Activity*
CCAAT/enhancer-binding protein α (C/EBPα), a basic leucine zipper transcription factor, is involved in mitotic growth arrest and… 
2000
2000
β-Catenin expression pattern in primary oesophageal squamous cell carcinoma. Relationship with clinicopathologic features and clinical outcome
Abstract. β-Catenin has an essential role in intercellular adhesion and signal transduction. β-catenin functions as a… 
1997
1997
DNA‐synthesis enzyme activity: A biological tool useful for predicting anti‐metabolic drug sensitivity in breast cancer?
Thymidine kinase (TK) and thymidylate synthase (TS) play a key role in, respectively, the salvage and the de novo DNA synthesis… 
1991
1991
Phosphonate-containing inhibitors of tyrosine-specific protein kinases.
Tyrosine-specific protein kinases (TPK) are important signal transducing enzymes involved in normal cellular growth and… 
Highly Cited
1990
Highly Cited
1990
PDGF-induced activation of phospholipase C is not required for induction of DNA synthesis.
Platelet-derived growth factor (PDGF) induction of DNA synthesis is believed to involve activation of phospholipase C (PLC) and… 
Highly Cited
1988
Highly Cited
1988
Characterization of receptor tyrosine-specific protein kinases by the use of inhibitors. Staurosporine is a 100-times more potent inhibitor of insulin receptor than IGF-I receptor.
Highly Cited
1988
Highly Cited
1988
Characterization of four tyrosine protein kinases from the particulate fraction of rat spleen.
Four distinct tyrosine protein kinases active on poly(Glu4,Tyr1) and angiotensin II, and operationally termed TPK-I, TPK-IIA, TPK… 
Highly Cited
1987
Highly Cited
1987
Polycation‐dependent, Ca2+‐antagonized phosphorylation of calmodulin by casein kinase‐2 and a spleen tyrosine protein kinase
1987
1987
Inhibition of tyrosine protein kinase by synthetic erbstatin analogs.
Sir: The effective synthesis of the specific tyrosine protein kinase (TPK) inhibitor, erbstatin (1), and its dihydroxy analogs… 
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