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surfactin synthetase

National Institutes of Health

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Bacterial Proteinspeptide synthase

Papers overview

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2016
2016
Characterization of a Bacillus subtilis surfactin synthetase knockout and antimicrobial activity analysis.
Highly Cited
2010
Highly Cited
2010
Functional dissection of surfactin synthetase initiation module reveals insights into the mechanism of lipoinitiation.
2008
2008
Activation of transcription initiation by Spx: formation of transcription complex and identification of a Cis‐acting element required for transcriptional activation
The Spx protein of Bacillus subtilis interacts with RNA polymerase (RNAP) to activate transcription initiation in response to… 
2000
2000
Recombinant acylheptapeptide lichenysin: high level of production by Bacillus subtilis cells.
Peptide synthetases are multi-domain proteins that catalyze the assembly, from amino acids and amino acid derivatives, of… 
1998
1998
Stoichiometry and specificity of in vitro phosphopantetheinylation and aminoacylation of the valine-activating module of surfactin synthetase.
Surfactin synthetase is the enzyme responsible for biosynthesis of the lipoheptapeptide antibiotic surfactin by Bacillus subtilis… 
1998
1998
Coordinate Transcription and Physical Linkage of Domains in Surfactin Synthetase Are Not Essential for Proper Assembly and Activity of the Multienzyme Complex*
Bacterial peptide synthetases have two common features that appear to be strictly conserved. 1) The enzyme subunits are co… 
1994
1994
Analysis of surfactin synthetase subunits in srfA mutants of Bacillus subtilis OKB105
The srfA operon of Bacillus subtilis functions in the biosynthesis of the lipopeptide antibiotic surfactin. On the basis of… 
1994
1994
Characterization of the surfactin synthetase isolated from the Bacillus subtilis strain producing iturin
SummaryThe lipopeptides, surfactin and iturin, are co-produced by B. subtilis. In this work, the three subunits of surfactin… 
1993
1993
Amino-acylation site mutations in amino acid-activating domains of surfactin synthetase: effects on surfactin production and competence development in Bacillus subtilis
The part of the srfA operon of Bacillus subtilis that contains the region required for competence development is composed of the… 
1993
1993
Analysis of a mutant amino acid‐activating domain of surfactin synthetase bearing a serine‐to‐alanine substitution at the site of carboxylthioester formation
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