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peptide synthase

Known as: Synthases, Peptide, Acid-Amino-Acid Ligases, Acid Amino Acid Ligases 
Ligases that catalyze the joining of adjacent AMINO ACIDS by the formation of carbon-nitrogen bonds between their carboxylic acid groups and amine… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (41)

2,3-Dihydroxybenzoate serine ligase4-dimethylamino-L-phenylalanine thioester N-methylating enzymeAtg3 protein, ratDihydrofolate synthase

Broader (1)

Carbon-Nitrogen Ligases
In BloodProcess of secretionacid-D-amino acid ligase activityantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
The thioesterase domain from the pimaricin and erythromycin biosynthetic pathways can catalyze hydrolysis of simple thioester substrates.
Highly Cited
2005
Highly Cited
2005
The Biosynthesis of Vancomycin‐Type Glycopeptide Antibiotics—A Model for Oxidative Side‐Chain Cross‐Linking by Oxygenases Coupled to the Action of Peptide Synthetases
Vancomycin (Scheme 1) and teicoplanin are “last resort” antibiotics for the treatment of severe infections with enterococci and… 
Highly Cited
2002
Highly Cited
2002
Plasmid-mediated iron uptake and virulence in Vibrio anguillarum.
Highly Cited
2001
Highly Cited
2001
Nonribosomal peptide synthetase genes occur in most cyanobacterial genera as evidenced by their distribution in axenic strains of the PCC
Abstract. Previous studies largely carried out with environmental samples or axenic and non-axenic cultures suggested that… 
2000
2000
Mutational Analysis of the N-Methyltransferase Domain of the Multifunctional Enzyme Enniatin Synthetase*
N-Methylcyclopeptides like cyclosporins and enniatins are synthesized by multifunctional enzymes representing hybrid systems of… 
1997
1997
Purification of peptide synthetases involved in pristinamycin I biosynthesis
Several assays of pristinamycin I synthetases based on adenylate or thioester formation were developed. Purification to near… 
Review
1996
Review
1996
Engineered biosynthesis of peptide antibiotics.
1994
1994
ATP binding in peptide synthetases: determination of contact sites of the adenine moiety by photoaffinity labeling of tyrocidine synthetase 1 with 2-azidoadenosine triphosphate.
Characterization of the nucleotide binding domain in peptide synthetases was approached by photoaffinity labeling of tyrocidine… 
1994
1994
Nucleotide binding by multienzyme peptide synthetases.
Peptide synthetases consist of linearly arranged catalytic units, which by sequence alignment show equally spaced amino-acid… 
Highly Cited
1993
Highly Cited
1993
Nucleotide sequence of 5' portion of srfA that contains the region required for competence establishment in Bacillus subtilus
The nucleotide sequence of the 20,535 base pairs of the 5' end of the srfA operon, containing the region required for competence… 
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