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peptide synthase

Known as: Synthases, Peptide, Acid-Amino-Acid Ligases, Acid Amino Acid Ligases 
Ligases that catalyze the joining of adjacent AMINO ACIDS by the formation of carbon-nitrogen bonds between their carboxylic acid groups and amine… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (41)

2,3-Dihydroxybenzoate serine ligase4-dimethylamino-L-phenylalanine thioester N-methylating enzymeAtg3 protein, ratDihydrofolate synthase

Broader (1)

Carbon-Nitrogen Ligases
In BloodProcess of secretionacid-D-amino acid ligase activityantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Chain Initiation in the Leinamycin-producing Hybrid Nonribosomal Peptide/Polyketide Synthetase from Streptomyces atroolivaceus S-140
Nonribosomal peptide natural products are biosynthesized from amino acid precursors by nonribosomal peptide synthetases (NRPSs… 
2005
2005
Utility of epimerization domains for the redesign of nonribosomal peptide synthetases
Many pharmacologically important agents are assembled on multimodular nonribosomal peptide synthetases (NRPSs) whose modules… 
2003
2003
Deletion of a Single Amino Acid Residue from Different 4-Coumarate:CoA Ligases from Soybean Results in the Generation of New Substrate Specificities*
Plant 4-coumarate:coenzyme A ligases, acyl-CoA ligases, peptide synthetases, and firefly luciferases are grouped in one family of… 
Highly Cited
2002
Highly Cited
2002
Plasmid-mediated iron uptake and virulence in Vibrio anguillarum.
2000
2000
Mutational Analysis of the N-Methyltransferase Domain of the Multifunctional Enzyme Enniatin Synthetase*
N-Methylcyclopeptides like cyclosporins and enniatins are synthesized by multifunctional enzymes representing hybrid systems of… 
1997
1997
Purification of peptide synthetases involved in pristinamycin I biosynthesis
Several assays of pristinamycin I synthetases based on adenylate or thioester formation were developed. Purification to near… 
Review
1996
Review
1996
Engineered biosynthesis of peptide antibiotics.
1994
1994
ATP binding in peptide synthetases: determination of contact sites of the adenine moiety by photoaffinity labeling of tyrocidine synthetase 1 with 2-azidoadenosine triphosphate.
Characterization of the nucleotide binding domain in peptide synthetases was approached by photoaffinity labeling of tyrocidine… 
1992
1992
Identification and characterization of phosphinothricin-tripeptide biosynthetic genes in Streptomyces viridochromogenes.
1992
1992
Cyclosporin synthetase is a 1.4 MDa multienzyme polypeptide Re‐evaluation of the molecular mass of various peptide synthetases
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