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Dihydrofolate synthase
Known as:
dihydrofolate synthetase
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
peptide synthase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents
M. V. Raimondi
,
O. Randazzo
,
+4 authors
S. Collina
Molecules
2019
Corpus ID: 85515060
Dihydrofolate reductase inhibitors are an important class of drugs, as evidenced by their use as antibacterial, antimalarial…
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Highly Cited
2017
Highly Cited
2017
Quantum mechanical, spectroscopic and docking studies of 2-Amino-3-bromo-5-nitropyridine by Density Functional Method.
C. Abraham
,
J. Prasana
,
S. Muthu
Spectrochimica acta. Part A, Molecular and…
2017
Corpus ID: 23275384
Highly Cited
2013
Highly Cited
2013
para-Aminosalicylic Acid Is a Prodrug Targeting Dihydrofolate Reductase in Mycobacterium tuberculosis♦
Jun Zheng
,
E. Rubin
,
+9 authors
L. Camacho
The Journal of Biological Chemistry
2013
Corpus ID: 6049085
Background: PAS is an antimycobacterial whose mechanism(s) of action remains elusive. Results: PAS is incorporated into the…
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2003
2003
The GLOBULAR ARREST1 gene, which is involved in the biosynthesis of folates, is essential for embryogenesis in Arabidopsis thaliana.
T. Ishikawa
,
C. Machida
,
Y. Yoshioka
,
H. Kitano
,
Y. Machida
The Plant journal : for cell and molecular…
2003
Corpus ID: 30632632
We identified a mutation in Arabidopsis that resulted in defective embryos, and we designated this mutation globular arrest1…
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Highly Cited
2001
Highly Cited
2001
Tetrahydrofolate biosynthesis in plants: Molecular and functional characterization of dihydrofolate synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana
S. Ravanel
,
H. Cherest
,
+4 authors
F. Rébeillé
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 5614262
Tetrahydrofolate coenzymes involved in one-carbon (C1) metabolism are polyglutamylated. In organisms that synthesize…
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2001
2001
A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria.
E. Salcedo
,
J. Cortese
,
C. Plowe
,
P. Sims
,
J. Hyde
Molecular and biochemical parasitology
2001
Corpus ID: 11219242
1995
1995
Isolation of dihydrofolate and folylpolyglutamate synthetase activities from Neurospora.
D. McDonald
,
I. Atkinson
,
E. Cossins
,
B. Shane
Phytochemistry
1995
Corpus ID: 30231784
1988
1988
Dihydrofolate synthetase and folylpolyglutamate synthetase: direct evidence for intervention of acyl phosphate intermediates.
R. Banerjee
,
B. Shane
,
J. McGuire
,
J. Coward
Biochemistry
1988
Corpus ID: 45291450
The transfer of 17O and/or 18O from (COOH-17O or -18O) enriched substrates to inorganic phosphate (Pi) has been demonstrated for…
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Highly Cited
1987
Highly Cited
1987
Primary structure of the Escherichia coli folC gene and its folylpolyglutamate synthetase-dihydrofolate synthetase product and regulation of expression by an upstream gene.
A. Bognar
,
C. Osborne
,
B. Shane
The Journal of biological chemistry
1987
Corpus ID: 24161256
Highly Cited
1979
Highly Cited
1979
The characteristics and significance of sulfonamides as substrates for Escherichia coli dihydropteroate synthase.
S. Roland
,
R. Ferone
,
R. Harvey
,
V. L. Styles
,
R. Morrison
The Journal of biological chemistry
1979
Corpus ID: 3202976
Sulfonamides are known to compete with p-aminobenzoic acid for dihydropteroate synthase. Others have reported that some…
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